Evidence map›Paper›PMID 40552017›Full record

ReviewDEN open2026

Endoscopic Ultrasound-guided Drainage With Lumen-apposing Metal Stent versus Plastic Stent for the Treatment of Pancreatic Pseudocyst: A Systematic Review and Meta-analysis.

André Orsini Ardengh, Thiago Arantes de Carvalho Visconti, Marcelo Klotz Dall'Agnol, Ygor Rocha Fernandes, Matheus de Oliveira Veras, Evellin Souza Valentim Dos Santos, Marcos Eduardo Lera do Santos, Sergio Eiji Matuguma, José Celso Ardengh, Wanderley Marques Bernardo and 1 more

Abstract readReview
In one paragraph

Review in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

André Orsini ArdenghGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.ORCID https://orcid.org/0000-0001-6373-5598
Thiago Arantes de Carvalho ViscontiGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.
Marcelo Klotz Dall'AgnolGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.
Ygor Rocha FernandesGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.ORCID https://orcid.org/0000-0002-8653-8658
Matheus de Oliveira VerasGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.
Evellin Souza Valentim Dos SantosGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.
Marcos Eduardo Lera do SantosGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.ORCID https://orcid.org/0000-0001-9759-3807
Sergio Eiji MatugumaGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.
José Celso ArdenghDigestive Endoscopy Service Hospital Moriah São Paulo Brazil.
Wanderley Marques BernardoGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.
Eduardo Guimarães Hourneaux de MouraGastroenterology Department, Gastrointestinal Endoscopy Unit, Hospital das Clínicas University of São Paulo (USP) Medical School São Paulo Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pancreatic pseudocyst (PP), following acute or chronic pancreatitis, may become symptomatic or persist beyond 6-8 weeks, requiring drainage. Endoscopic ultrasonography-guided drainage (EUS-D) is the preferred method, using double pigtail plastic stents (DPPS) or self-expandable metallic stents (SEMS), such as lumen-apposing metal stents (LAMS). This meta-analysis compares DPPS and LAMS in EUS-D for PP, focusing on technical success, clinical success, adverse events (AEs), recurrence, and procedure time. Methods: A search strategy was conducted in MEDLINE, Embase, Lilacs, and Cochrane databases according to PRISMA guidelines. Random-effect models were used for statistical analysis based on intention-to-treat. Heterogeneity was assessed using the I Results: Ten studies were included: one prospective cohort and nine retrospective cohorts, conducted between 2014 and 2024. A total of 502 patients with PP were treated with EUS-D. The clinical success rate was higher using LAMS (Risk ratio [RR] = 1.05; 95% confidence interval [CI]: 1.01; 1.09; I Conclusion: The study demonstrated that LAMS has a higher clinical success rate and a shorter procedure time compared to DPPS. There is no difference in terms of early and late AEs, recurrence, and technical success.

Indexed as

double pigtail plastic stentsendoscopic ultrasonography‐guided drainageendosonographylumen‐apposing metal stentspancreatic pseudocyst

Identifiers

PMID40552017
PMCPMC12182979

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.