Evidence map›Paper›PMID 40551950›Full record

ArticleCureus2025

Post-Anaphylaxis Adrenaline-Induced Takotsubo Cardiomyopathy: A Case Report.

Zahid Khan, Fady Eldabe, Konstantinos Tyrovolas, Krishna Rathod, Paul Rees

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zahid KhanAcute Medicine, Mid and South Essex NHS Foundation Trust, Southend-on-Sea, GBR.
Fady EldabeCardiology, Barts Heart Centre, London, GBR.
Konstantinos TyrovolasCardiology, Barts Heart Centre, London, GBR.
Krishna RathodCardiology, Barts Heart Centre, London, GBR.
Paul ReesCardiology, Barts Heart Centre, London, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo cardiomyopathy (TCM) is an acute and reversible cardiac condition triggered by an adrenaline rush in response to stress that is characterised by apical ballooning of the left ventricle in the absence of coronary artery obstruction. Although the exact pathophysiology remains unclear, it is believed to be secondary to the release of adrenaline or catecholamine in response to stress. We present the case of a 71-year-old female who presented to a district general hospital (DGH) at approximately 1700 pm in the evening with signs and symptoms of anaphylaxis following the consumption of pistachios the night before. She woke up with mild shortness of breath (sob) in the morning at 0900 am. The symptoms progressively got worse after midday, and she developed throat tightness and mild tongue swelling at 1600, prompting her to attend the local hospital's accident and emergency department. Following evaluation in the accident and emergency department, she was given 0.5 mg of adrenaline one in 1000 (1 mg/mL) solution intramuscularly for a delayed allergic reaction to pistachios. She developed central chest pain and tightness within minutes of receiving the intramuscular adrenaline, and an electrocardiogram showed ST elevation in the lateral leads and ST depression inferiorly. She was transferred to our cardiac centre for emergency coronary angiography, and bedside echocardiography revealed mild to moderate left ventricular systolic dysfunction (LVSD). Coronary angiography via the right radial access showed unobstructed coronaries. Left ventriculogram (LVG) post-angiogram demonstrated apical ballooning suggestive of TCM secondary to adrenaline administration for anaphylaxis to pistachio. Departmental echocardiography revealed a mild LVSD with an ejection fraction of 45%. She was started on bisoprolol in addition to her regular medications. Echocardiography demonstrated normal left ventricular function three months later, and the patient was discharged from the outpatient clinic.

Indexed as

adrenaline autoinjectoradrenaline induced takosubo cardiomyopathyallergy to fooddrug induced anaphylaxislv gramnormal coronary angiogrampistachio induced anaphylaxisst-elevation myocardial infarction (stemi)takotsubo cardioyopathytrans thoracic echocardiography

Identifiers

PMID40551950
PMCPMC12183530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.