Evidence map›Paper›PMID 40551946›Full record

ArticleCureus2025

Acute Hemianopia Associated With Nonketotic Hyperglycemia: A Case Report With Advanced Neuroimaging Findings.

Honami Tanifuji, Kouhei Kamiya, Genki Sato, Arisa Yoshida, Masaaki Hori

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Honami TanifujiDepartment of Radiology, Toho University Graduate School of Medicine, Tokyo, JPN.
Kouhei KamiyaDepartment of Radiology, Toho University Graduate School of Medicine, Tokyo, JPN.
Genki SatoDepartment of Diabetes,Metabolism and Endcrinology, Toho University Graduate School of Medicine, Tokyo, JPN.
Arisa YoshidaDepartment of Diabetes,Metabolism and Endcrinology, Toho University Graduate School of Medicine, Tokyo, JPN.
Masaaki HoriDepartment of Radiology, Toho University Graduate School of Medicine, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonketotic hyperglycemia (NKH) can present with acute neurological symptoms such as tremor, ballismus, seizures, hemianopia, and coma, and may be associated with abnormal signal intensities on brain MRI. We report the case of a woman in her 50s with poorly controlled diabetes mellitus (HbA1c 15.9%) who was admitted with a chief complaint of right homonymous hemianopia. No other neurological deficits were observed. At presentation, the patient's blood glucose level was markedly elevated (608 mg/dL), with a blood pH of 7.36, negative ketone bodies, and an increased serum osmolality of 301 mOsm/L, consistent with a diagnosis of nonketotic hyperglycemia (NKH). Brain MRI performed on the day of admission revealed subcortical hypointensities in the left occipital and parietal lobes on T2-weighted images (T2WI). Arterial spin labeling (ASL) demonstrated increased perfusion in the corresponding areas. Proton magnetic resonance spectroscopy (¹H-MRS) showed a reduction in N-acetylaspartate (NAA) levels in the same region. Following glycemic control, her visual field deficits improved, and the subcortical MRI abnormalities resolved. Given the temporal correlation between symptom resolution and imaging normalization, the patient was diagnosed with NKH-induced hemianopia with transient MRI abnormalities. While subcortical T2 hypointensities are a known radiologic feature of NKH, associated findings on ASL and ¹H-MRS have been rarely documented. We present this case alongside a review of the relevant literature.

Indexed as

arterial spin labeling (asl)magnetic resonance spectroscopy (mrs)nonketotic hyperglycemiasingle-photon emission computed tomographyt2-weighted imagingvisual field disorder

Identifiers

PMID40551946
PMCPMC12183348

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