ArticleCureus2025
Amniotic Fluid Embolism in Donor Egg Twin Pregnancy: A Clinical Challenge in Critical Care.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amniotic fluid embolism (AFE) is a rare but life-threatening obstetric emergency marked by respiratory distress, severe hypotension, and coagulopathy with haemorrhage. This case involves a 45-year-old nulliparous woman with a dichorionic diamniotic twin pregnancy via in vitro fertilisation (IVF) with a donor egg. At 36 weeks' gestation, the patient developed sudden respiratory distress following the detection of persistent maternal tachycardia. Cardiotocography (CTG) revealed foetal distress, necessitating an emergency caesarean section, which resulted in the delivery of two live neonates. Her postpartum course was complicated by haemorrhage managed with a vaginal balloon and a second episode of respiratory distress with hypoxia. Admitted to the intensive care unit (ICU) for supportive care, she recovered well. Further investigations excluded pulmonary embolism and infection. Whilst peripartum cardiomyopathy (PPCM) was considered, the presence of massive haemorrhage and disseminated intravascular coagulation (DIC) strongly suggested AFE. This case highlights AFE's rare occurrence in an IVF pregnancy and supports the emerging hypothesis that conception through donor eggs may pose a significant, under-recognised immunologic risk for AFE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.