Evidence map›Paper›PMID 40551928›Full record

ArticleCureus2025

An Extremely Rare Case of Squamous Cell Carcinoma Following Treatment for External Auditory Canal Papilloma.

Yumi Ohta, Yoshiyuki Ozono, Motoyuki Suzuki, Takashi Sato, Hidenori Inohara

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yumi OhtaDepartment of Otorhinolaryngology-Head and Neck Surgery, National Hospital Organization Osaka Medical Center, Osaka, JPN.
Yoshiyuki OzonoDepartment of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka Faculty of Medicine, Suita, JPN.
Motoyuki SuzukiDepartment of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka Faculty of Medicine, Suita, JPN.
Takashi SatoDepartment of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka Faculty of Medicine, Suita, JPN.
Hidenori InoharaDepartment of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka Faculty of Medicine, Suita, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The case is of a 60-year-old woman with a history of radiotherapy for parotid adenoid cystic carcinoma. Twenty years after irradiation, a papilloma developed in the left external auditory canal. Nine years after excision of the papilloma, a squamous cell carcinoma developed in the same region. This is a rare case of squamous cell carcinoma following treatment for a papilloma and is considered radiation-induced cancer. Because re-irradiation is not possible as a treatment for radiation-induced cancer, it is necessary to diagnose the cancer early so that curative resection is possible. Multiple biopsies should be considered when malignancy is suspected because a single biopsy may not be sufficient to diagnose an auditory canal tumor.

Indexed as

external auditory canalhuman papilloma virusradiation-induced cancersquamous cell carcinomasquamous papilloma

Identifiers

PMID40551928
PMCPMC12185161

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.