Evidence map›Paper›PMID 40551857›Full record

ArticleCase reports in ophthalmology

Juvenile Ocular Myasthenia Gravis in a 3-Year-Old African Girl: A Case Report.

Elisamia Ngowi, Humrath Lusheke, Rashid Mbuma, Zeenat Juneja, Mayila Mbuki, Sheliza Parvez Thaver, Tatenda Magodi, Rukhsar Osman, Hajaj Salum

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In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Elisamia NgowiDepartment of Paediatrics and Child Health, Aga Khan Hospital Tanzania, Dar es Salaam, Tanzania.
Humrath LushekeDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.
Rashid MbumaDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.
Zeenat JunejaDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.
Mayila MbukiDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.
Sheliza Parvez ThaverDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.
Tatenda MagodiDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.
Rukhsar OsmanDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.
Hajaj SalumDepartment of Paediatrics and Child Health, Aga Khan University, Dar es Salaam, Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Myasthenia gravis (MG) is an autoimmune disorder causing muscle weakness. When diagnosed before 18, it is termed juvenile MG. Ocular symptoms are more common in children than adults. Diagnosis of ocular MG involves tests like the ice pack test, while treatment includes cholinesterase inhibitors and corticosteroids. Case Presentation: We present a case of a 3-year-old girl who had a 2-month history of progressive weakness of both eyelids, but no other body weakness reported. She was diagnosed with ocular MG after a positive ice pack test and detection of autoantibodies against acetylcholine receptors. She was started on pyridostigmine and later added cyclosporine, and her symptoms improved greatly afterward. Conclusion: Ocular MG is rare. This case report highlights the challenges of diagnosing and managing ocular MG in low-resource settings, stressing the need for early recognition and treatment.

Indexed as

Acetyl-choline receptorsAutoimmuneOcular myasthenia gravisPtosis

Identifiers

PMID40551857
PMCPMC12185059

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