ReviewInternational journal of general medicine2025
Advances in the Treatment and Clinical Management Strategies of Tuberculous Meningitis.
Review in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculous meningitis (TBM), a central nervous system infection caused by Mycobacterium tuberculosis, is a rapidly progressing, insidious disease with an exceptionally high disability and mortality rate. Its significant global burden has become a critical focus in public health. The clinical diagnosis of TBM faces challenges due to the lack of specific symptoms and imaging characteristics, making early detection difficult. Combined with the shielding effect of the blood-brain barrier against anti-tuberculosis drugs and the issue of drug resistance, treatment outcomes are often suboptimal. Furthermore, current early sensitive diagnostic tools are inadequate, leading to delayed treatment for many patients and adversely affecting their prognosis. This paper reviews the pathophysiological mechanisms of TBM, the types and mechanisms of action of therapeutic drugs, and the common drug selection issues and safety challenges encountered in clinical practice. The aim is to provide comprehensive guidance and references for clinical diagnosis and treatment to improve the therapeutic outcomes and quality of life for TBM patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.