Evidence map›Paper›PMID 40551692›Full record

ReviewCurrent pharmaceutical design2026

Corticosteroids for Nerve Regeneration: A Narrative Review.

Mohammed H Karrar Alsharif, Nagi M Bakhit, Juman M Almasaad, Mehmet Emin Onger

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A review of new developments in peripheral nerve regeneration.Biochemistry and biophysics reports · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammed H Karrar AlsharifDepartment of Basic Medical Science, College of Medicine, Prince Sattam Bin Abdulaziz University, Al Kharj, 11942, Saudi Arabia.
Nagi M BakhitAnatomy Department, College of Medicine, Arabian Gulf University, Manama, Bahrain.
Juman M AlmasaadDepartment of Basic Medical Sciences, College of Medicine, King Saud Bin Abdul Aziz University for Health Sciences, National Guard Health Affairs, Jeddah, Saudi Arabia.
Mehmet Emin OngerDepartment of Histology & Embryology, Medical Faculty, Ondokuz Mayis University, Samsun, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the use of advanced microsurgical techniques, around one-third of peripheral nerve injuries still show inadequate functional regeneration and incomplete healing. Peri- and intraneural nerve damage leads to pathophysiologic alterations, including morphological and metabolic changes, where the nerve is disrupted. Animal research shows no proven adjustment drugs for peripheral nerve regeneration, but studies suggest medicines can speed up regeneration using functional and histological parameters after nerve injury. Factors affecting nerve regeneration effectiveness include injury type, age, regeneration time, procedures, and materials. Complete regeneration and functional recovery are rarely achieved, regardless of the kind of pharmaceutical therapy used, necessitating further research into nerve regeneration. Future research could enhance corticosteroid doses with additional drugs, increasing clinical use. This review explores the mechanism of action of corticosteroids Dexamethasone, Betamethasone, and Methylprednisolone in peripheral nerve regeneration experiments, highlighting the potential for enhanced nerve injury.

Indexed as

Adrenal Cortex HormonesNerve RegenerationPeripheral Nerve InjuriesAnimalsHumansAdrenal Cortex Hormonesbetamethasonecentral nervous system.dexamethasonemethylprednisolonenerve injuryPeripheral nerve regeneration

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.