Evidence map›Paper›PMID 40551446›Full record

ArticleAnalytical chemistry2025

4D-Printed Redox-Responsive Needle-Flow Reactors Enabling Online Quantitative Profiling of Living Rat Brain Extracellular Lactate and Glucose.

Hsiao-Chu Chiu, Cheng-Kuan Su

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Dose Optimization of Tilmicosin againstJournal of agricultural and food chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hsiao-Chu ChiuDepartment of Chemistry, National Chung Hsing University, Taichung 402202, Taiwan, R.O.C.
Cheng-Kuan SuDepartment of Chemistry, National Chung Hsing University, Taichung 402202, Taiwan, R.O.C.ORCID 0000-0003-1306-9202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various assays are performed based on the use of oxidase-based derivatization schemes coupled with chromogenic or fluorogenic reagents and spectrometric determination. To enable online quantitative profiling of living rat brain extracellular glucose and lactate without requiring a spectrophotometer or fluorometer, a flow reactor with a redox-responsive needle is fabricated using the digital light processing four-dimensional printing (4DP) technique and photocurable resins incorporating 2,2'-(ethylenedioxy)diethanethiol (EDT). Upon exposure to hydrogen peroxide (H

Indexed as

BrainGlucoseLactic AcidPrinting, Three-DimensionalAnimalsHydrogen PeroxideMicrodialysisMixed Function OxygenasesNeedlesOxidation-ReductionRatsGlucoseHydrogen Peroxidelactate 2-monooxygenaseLactic AcidMixed Function Oxygenases

Identifiers

PMID40551446
PMCPMC12311888

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.