Evidence map›Paper›PMID 40551281›Full record

SynthesisGlobal health research and policy2025

Prevalence of Tuberculosis among migrants under national screening programs: a systematic review and meta-analysis.

Qin Chen, Ningjun Ren, Shengya Liu, Zixin Qian, Mengdie Li, Aliyu Mustapha, Wei Luo, Jinghua Li, Wenxi Wang, Chun Hao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Global health research and policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qin Chen *Department of Medical Statistics, School of Public Health, Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Ningjun Ren *Department of Medical Statistics, School of Public Health, Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Shengya LiuShenzhen International Travel Health Care Center (Shenzhen Customs District Port Outpatient Clinics), Shenzhen Customs District, Shenzhen, 518033, People's Republic of China.
Zixin QianDepartment of Medical Statistics, School of Public Health, Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Mengdie LiDepartment of Medical Statistics, School of Public Health, Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Aliyu MustaphaDepartment of Medical Statistics, School of Public Health, Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Wei LuoGuangzhou International Travel Healthcare Center, Guangzhou, 510130, People's Republic of China.
Jinghua LiDepartment of Medical Statistics, School of Public Health, Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Wenxi WangThe First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, 510000, People's Republic of China. danywwx@163.com.
Chun HaoDepartment of Medical Statistics, School of Public Health, Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China. haochun@mail.sysu.edu.cn.

Funding

Fundamental Research Funds for the Central Universities, Sun Yat-sen University 24ykqb007Guangdong Basic and Applied Basic Research Foundation 2023A1515030093
6 · The paper itself

Abstract

backgroundTuberculosis (TB) continues to pose a significant global public health threat, particularly among migrant populations. Screening policies exist in many receiving countries but differ markedly, and there is limited pooled evidence on TB and latent TB infection (LTBI) prevalence among migrants under different screening frameworks. This systematic review and meta-analysis aims to synthesize TB and LTBI prevalence among migrants and compared national screening policies to inform evidence-based public health planning.

methodsPubMed, Embase, Web of Science and Cochrane Library were searched for studies published 2016-2023. Random-effects models generated pooled prevalence estimates with 95% CIs; subgroup analyses examined differences by screening stage, migrant category, and country-of-origin incidence. Sensitivity analyses tested robustness. Government and health-agency websites were systematically examined and scored to table national TB-screening requirements.

results36 studies (26 TB, 21 LTBI) covering 40,738,331 migrants screened met inclusion criteria. The Pooled TB prevalence was 214.52/100,000 (95% CI 112.18-349.66) and LTBI prevalence 14.9% (95% CI 9.91-20.60). Countries employing both pre-entry screening and subsequent post-entry surveillance achieved the lowest TB prevalence (94.09/100,000). The highest burdens occurred among refugees/asylum seekers (439.25/100,000) and migrants from countries with TB incidence 300-499/100,000 (491.96/100,000). LTBI was most common when identified through post-entry screening (21.90%), those with multiple migrants (18.11%), and among migrants originating from countries with ≥ 500/100,000 TB incidence (30.90%). Policy comparison showed pre-entry screening is almost universal; the United States is the only country mandating systematic LTBI screening. Screening-scope scores were highest in traditional immigrant countries (16-20), intermediate in middle-income destinations such as China and Malaysia (10-14), and lowest in Nordic (4-8).

conclusionsThis study emphasizes the importance of targeted TB screening, especially for migrants from high-prevalence regions and at-risk populations. Comprehensive pre- and post-entry TB screening, along with strengthened latent TB screening and surveillance for diverse migrant populations, is essential. Meanwhile enhanced collaboration to update screening policies are key to achieving the goal of TB eradication and provide practical insights for effective TB control.

Indexed as

Latent TuberculosisMass ScreeningTransients and MigrantsTuberculosisHumansPrevalenceMeta-analysisMigrantsPolicy comparisonTuberculosis screening

Identifiers

PMID40551281
PMCPMC12183900

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.