Evidence map›Paper›PMID 40551255›Full record

ArticleJournal of anesthesia, analgesia and critical care2025

Patterns of lung aeration assessed through electrical impedance tomography in paediatric patients undergoing elective surgery: insights from a prospective and observational data-registry.

Daniela Rosalba, Grazia Meneghetti, Federico Verdina, Chiara Solai, Danila Azzolina, Laura Petronio, Matteo Guaraglia, Raffaella Buscaglia, Giulio Saviolo, Gaia Furlan and 14 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of anesthesia, analgesia and critical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06370507 (Ventilation Monitoring by Electrical Impedance Tomography During Anesthesia for Pediatric Surgery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06370507 unknown statusnot on this map

Ventilation Monitoring by Electrical Impedance Tomography During Anesthesia for Pediatric Surgery: an Observational Prospective Data-registry

Typeobservational_patient_registrySponsorAzienda Ospedaliero Universitaria Maggiore della CaritaRan2024 to 2025Enrolled800ConditionsVentilator Lung, Surgery, PediatricArmsElectrical impedance tomography assessment of ventilation distribution in course of sedation/general anesthesia for pediatric surgery
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Daniela Rosalba *Department of Traslational Medicine, Università del Piemonte Orientale, Novara, Italy.
Grazia Meneghetti *Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria "Maggiore Della Carità", Novara, Italy.
Federico VerdinaDepartment of Traslational Medicine, Università del Piemonte Orientale, Novara, Italy.
Chiara SolaiDepartment of Traslational Medicine, Università del Piemonte Orientale, Novara, Italy.
Danila AzzolinaDepartment of Ambiental Science and Prevention, Università Degli Studi Di Ferrara, Ferrara, Italy.
Laura PetronioAnaesthesia and Intensive Care, Ospedale Sant'Andrea, Vercelli, Italy.
Matteo GuaragliaAnaesthesia and General Intensive Care, Azienda Ospedaliero Universitaria Di Alessandria, Alessandria, Italy.
Raffaella BuscagliaAnaesthesia and Intensive Care, Azienda Ospedaliero Universitaria "Maggiore Della Carità", Novara, Italy.
Giulio SavioloDepartment of Traslational Medicine, Università del Piemonte Orientale, Novara, Italy.
Gaia FurlanAnaesthesia and General Intensive Care, Azienda Ospedaliero Universitaria Di Alessandria, Alessandria, Italy.
Filippo ViettiAnaesthesia and General Intensive Care, Azienda Ospedaliero Universitaria Di Alessandria, Alessandria, Italy.
Daniele BiasucciDepartment of Clinical Science and Translational Medicine, Tor Vergata' University of Rome, Rome, Italy.
Savino SpadaroDepartment of Traslational Medicine, Unversità Degli Studi Di Ferrara, Ferrara, Italy.
Rachele SimonteDepartment of Medicine and Surgery, University of Perugia, Perugia, Italy.
Edoardo De RobertisDepartment of Medicine and Surgery, University of Perugia, Perugia, Italy.
Federico LonghiniDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Serena PenpaResearch and Innovation Department (DAIRI), Azienda Ospedaliero Universitaria Di Alessandria, Alessandria, Italy.
Michele UbertazziPediatric Surgery, Azienda Ospedaliero Universitaria "Maggiore Della Carità", Novara, Italy.
Elena PanuccioPediatric Ortho-Trauma Surgery, Azienda Ospedaliero Universitaria "Maggiore Della Carità", Novara, Italy.
Paolo AluffiENT Division, Azienda Ospedaliero Universitaria "Maggiore Della Carità", Novara, Italy.
Stefano De CillàEye Clinic, Azienda Ospedaliero Universitaria "Maggiore Della Carità", Novara, Italy.
Matteo BrucoliMaxillofacial Surgery, Azienda Ospedaliero Universitaria "Maggiore Della Carità", Novara, Italy.
Rosanna VaschettoDepartment of Traslational Medicine, Università del Piemonte Orientale, Novara, Italy.
Gianmaria CammarotaDepartment of Traslational Medicine, Università del Piemonte Orientale, Novara, Italy. gianmaria.cammarota@uniupo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of anaesthesia on lung function during paediatric surgery remains an area of active investigation. Understanding respiratory mechanics under different anaesthetic approaches is crucial for optimising pulmonary management in this vulnerable population.

objectiveTo assess ventilation distribution changes during different phases of anaesthesia in paediatric patients, using electrical impedance tomography (EIT).

methodsThis observational study included 76 paediatric surgical patients-57 under controlled mechanical ventilation (CMV) and 19 breathing spontaneously. EIT assessed lung ventilation at multiple timepoints (T1-T6), analyzing regional distribution (ROIs) and center of ventilation (CoV).

resultsIn the CMV group, ventilation progressively shifted toward ventral lung regions (p < 0.0001 from T1 to T2, T3, T4, T5) with a contemporaneously reduced ventilation switching from T1 to T2 (p = 0.005), T3 (p < 0.0001), T4 (p = 0.001), and T5 (p < 0.0001). Ventilation normalised upon restoration of spontaneous breathing at the end of surgery. In the same group, CoV shifted toward non-dependent lung regions from T1 to T2, T3, T4, and T5 (p < 0.0001) and returned to baseline at T6. Overall, no modifications were observed in the spontaneous breathing group.

conclusionsIn paediatric surgical patients, contrariwise to spontaneous breath where no modifications occurred, CMV induced a progressive redistribution of ventilation towards the ventral lung regions, at the expense of the dorsal zones. These changes were reversible with the recovery of spontaneous breathing.

trial registrationNCT06370507.

Indexed as

Electrical impedance tomographyMechanical ventilationMonitoringPediatricsSpontaneous breathing

Identifiers

PMID40551255
PMCPMC12183812

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.