Evidence map›Paper›PMID 40551193›Full record

ArticleDiabetology & metabolic syndrome2025

The association of calf circumference with nutritional risk and mortality in type 2 diabetes aged over 80 years inpatient Chinese.

Chenxi Ren, Yunxia Zhu, Jun Tao, Xiaoyan Zhang

Abstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Chenxi Ren *Department of Geriatrics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Yunxia Zhu *Department of Geriatrics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Jun TaoDepartment of Geriatrics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Xiaoyan ZhangDepartment of Geriatrics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. zhangxy971088@hotmail.com.

Funding

Shanghai Municipal Health Commission 202340173
6 · The paper itself

Abstract

objectiveThe aim of this study was to determine whether low calf circumference (CC) could predict nutritional risk and the cut-off value of CC in type 2 diabetes (T2D) older patients. We also aimed to evaluate the risk factors for predicting mortality in T2D.

methodsA total of 296 older patients with T2D were enrolled in this study and followed for 2.5 years at the longest.

resultsThe CC level was significantly lower in the nutritional risk group than in the non-nutritional risk with T2D group (26.7 ± 4.1 cm vs. 30.2 ± 3.9 cm, P < 0.001). Decreased CC (OR, 6.79; 95% CI, 2.73–16.84; P < 0.001) and a new insulin resistance index of triglyceride glucose (TyG) (OR, 2.14; 95% CI, 1.13–4.07; P = 0.020) were independent risk factors for nutritional risk. The best CC cut-off value for predicting nutritional risk was 27.8 cm. Decreased CC (HR, 2.98; 95% CI, 1.40–6.33; P = 0.005) remained an independent risk factor for mortality.

conclusionDecreased CC could predict not only nutritional risk but also mortality in T2D patients aged over 80 years. CC may be a valuable index to screen out this population in T2D. The prevention strategy for diabetes patients should shifts gradually from the prevention of metabolic disorders to the muscle mass loss.

Indexed as

Calf circumferenceMortalityNRS 2002Nutritional riskType 2 diabetes

Identifiers

PMID40551193
PMCPMC12183836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.