ArticleImplementation science : IS2025
Methodological recommendations for assessing the impact of adaptations on outcomes in implementation research.
Article in Implementation science : IS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Using multi-method approaches to document and assess adaptations in a community-driven COVID-19 testing program.Implementation science communications · 2026Article
- Multi-method, longitudinal documentation of adaptations and their impact in the Accelerating Colorectal Cancer Screening and Follow-up through Implementation Science San Diego colorectal cancer screening implementation study.Translational behavioral medicine · 2026Article
- The costs of partner engagement in research: Opportunities for pragmatic research, implementation science, and the science of engagement.Journal of clinical and translational science · 2026Article
- Developing a digital ecological momentary assessment tool for 'real time' evaluation in implementation science: testing through evaluation of a novel digital social prescribing intervention.Frontiers in public health · 2026Article
- Competency-Based Health Professions Education in Evolution: Challenges and Adaptations After Implementation.Perspectives on medical education · 2026Article
- Documenting adaptations across the Accelerating Colorectal Cancer Screening and follow-up through Implementation Science research programs: methods and adaptation examples.Frontiers in health services · 2025Article
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4 authors.
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Abstract
backgroundA major gap in implementation research is guidance for designing studies to assess the impact of adaptations to interventions and implementation strategies. Many researchers regard experimental designs as the gold standard. However, the possible study designs for assessing the impact of adaptation on implementation, service and person-level outcomes is broad in scope, including descriptive and correlational research and variations of randomized controlled trials. This article provides a set of key methodological recommendations for assessing the impact of adaptations to interventions and implementation strategies on implementation outcomes. RECOMMENDATIONS: We offer four key recommendations for investigating the impact of adaptations on implementation outcomes. First, we recommend defining the construct of adaptations and identifying the type and timing of adaptations. Second, we recommend that study teams identify the expected proximal and distal outcomes of adaptations. Third, we recommend that study teams consider all possible study design options and select the design that is best suited to answer the research question(s), and is feasible given practical and technical constraints, and acceptable to research partners and participants. Fourth, we recommend that study teams consider the type of adaptation and outcome data available, the goals of the adaptation study, and the complexity of the study design when selecting analytic approaches. We provide materials and examples related to the four key recommendations to help study teams plan and conduct adaptation studies.
conclusionsThis article provides methodological recommendations for assessing the impact of adaptations to interventions and implementation strategies on implementation, service, and person-level outcomes that are grounded in the practical realities of implementation research. Increasing the number of studies examining how, which, and under what conditions adaptations are associated with mechanisms and outcomes will advance research on adaptation.
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