ArticleJournal of orthopaedic surgery and research2025
An innovative minimally invasive technique for lumbar adjacent segment disease: a retrospective comparative analysis between extreme-oblique lumbar interbody fusion combined with percutaneous endoscopic lumbar discectomy(XOLIF-PELD) and posterior lumbar interbody fusion(PLIF) revision.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Efficacy comparison of arthroscopic-assisted uniportal spinal surgery and percutaneous endoscopic discectomy for adjacent segment lumbar disc herniation after fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Early Outcomes of Unilateral Biportal Endoscopic Decompression for Adjacent Segment Disease After Lumbar Fusion.Journal of pain research · 2025Article
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8 authors.
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Abstract
purposeThis study evaluates An Innovative Minimally Invasive Technique using extreme-oblique lumbar interbody fusion combined with percutaneous endoscopic lumbar discectomy (XOLIF + PELD) versus posterior lumbar interbody fusion (PLIF) for lumbar adjacent segment disease(ASD) treatment.
methodsWe retrospectively analyzed 58 patients (26 treated with the combined technique, 32 with posterior fusion) with minimum 24-month follow-up. Clinical outcomes (Visual Analogue Scale(VAS), Oswestry Disability Index(ODI), Short Form-36(SF-36)), radiological parameters, and perioperative data including operative time, blood loss, hospital stay, and time to mobilization were assessed. Statistical analysis was performed using paired and independent t-tests or non-parametric equivalents with significance level set at p < 0.05.
resultsBoth groups showed significant clinical and radiological improvements. The XOLIF + PELD group demonstrated advantages in operative time (108.1 ± 21.4 vs. 192.8 ± 55.6 min), blood loss (45.3 ± 11.2 vs. 308.8 ± 108.7mL), hospital stay (2 vs. 6 days), postoperative mobilization (1 vs. 4 days), and minor complication rates (11.5% vs. 28.1%). Fusion rates were comparable (96.1% vs. 90.6%).
conclusionThe combined extreme-oblique lumbar interbody fusion with percutaneous endoscopic lumbar discectomy(XOLIF-PELD) approach may offer a minimally invasive alternative to posterior lumbar interbody fusion(PLIF) for selected patients with adjacent segment disease, demonstrating reduced surgical trauma, faster recovery, and fewer minor complications in this retrospective analysis.Despite study limitations inherent to retrospective analyses, these promising results warrant further investigation through prospective multicenter trials.
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