Evidence map›Paper›PMID 40551125›Full record

ArticleJournal of orthopaedic surgery and research2025

Magnetic resonance imaging in the evaluation of different compression locations in patients with cervical spondylotic radiculopathy.

Yu Wang, Xiaolong Chen, Xiang-Yu Li, Dongfan Wang, Dongdong Rong, Zheng Sun, Jie Lu, Shibao Lu

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yu Wang *Department of Orthopaedics, Xuanwu Hospital Capital Medical University, No.45 Changchun Street, Xicheng District, Beijing, 100053, China. wy19780630@163.com.
Xiaolong Chen *Department of Orthopaedics, Xuanwu Hospital Capital Medical University, No.45 Changchun Street, Xicheng District, Beijing, 100053, China. chensmalldragon@163.com.
Xiang-Yu LiDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, No.45 Changchun Street, Xicheng District, Beijing, 100053, China.
Dongfan WangDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, No.45 Changchun Street, Xicheng District, Beijing, 100053, China.
Dongdong RongDepartment of Radiology, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Zheng SunDepartment of Radiology, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Jie LuDepartment of Radiology, Xuanwu Hospital Capital Medical University, Beijing, 100053, China. imagingluji@hotmail.com.
Shibao LuDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, No.45 Changchun Street, Xicheng District, Beijing, 100053, China. spinelu@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStudies showed that T2-weighted turbo spin-echo SPACE (T2-SPACE) could be superior to conventional two-dimensional magnetic resonance imaging (2D MRI) to detect the locations of nerve root compression. However, there is a lack of evidence in patients with cervical spondylotic radiculopathy (CSR). This study aims to evaluate the diagnostic value of contrast‑enhanced 3D T2-SPACE sequence in patients with CSR.

methodsThis cohort study enrolled 80 adult CSR patients from October 2021 to May 2023. Patients were allocated into 2D MRI positive and negative groups based on the findings of accurate location of nerve root compression. The nerve root compression diagnostic value was evaluated on 2D MRI, contrast‑enhanced 3D T2-SPACE MRI, and surgical findings. Cervical lordosis, the height of the foramina, and the proximal tilting angle of the nerve root (PTA) were measured.

resultsOf the 80 patients, 69 patients were diagnosed correctly by 2D MRI, and 11 patients were correctly diagnosed by contrast-enhanced 3D T2-SPACE MRI. Of those, 0 were false-positive and 9 patients were false-negative compression. Seven out of eleven patients from 2D MRI- group located nerve root compression at foraminal area and the other 4 located nerve root compression at lateral zone. All the negative cases in 2D MRI were correctly diagnosed by contrast-enhanced 3D T2-SPACE MRI. Larger PTAs could be indicators for the diagnosis of foraminal nerve root compression.

conclusionOur results showed that contrast-enhanced 3D T2-SPACE MRI was more accurate than 2D MRI for detecting nerve root compression in patients with CSR. The contrast-enhanced 3D T2-SPACE could better visualize the nerve root compression intra- and extra-foramina than conventional 2D MRI.

Indexed as

Cervical VertebraeMagnetic Resonance ImagingRadiculopathySpondylosisAdultAgedCohort StudiesFemaleHumansImaging, Three-DimensionalMaleMiddle AgedCervical radiculopathyDiagnosisMagnetic resonance imageThree-dimension

Identifiers

PMID40551125
PMCPMC12186394

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.