Evidence map›Paper›PMID 40551121›Full record

ArticleHarm reduction journal2025

Highlighting variability in fentanyl test strip instructions using thematic content analysis.

Cianna J Piercey, Claire L Pince, Hollis C Karoly

Abstract read
In one paragraph

Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cianna J PierceyDepartment of Psychology, Colorado State University, 1876 Campus Delivery, Fort Collins, CO, 80523-1876, USA. Cianna.Piercey@colostate.edu.
Claire L PinceDepartment of Psychology, Colorado State University, 1876 Campus Delivery, Fort Collins, CO, 80523-1876, USA.
Hollis C KarolyDepartment of Psychiatry, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Funding

Exploring the Effects of Cannabinoids on Alcohol Consumption and the Microbiota-Gut-Brain AxisK23AA028238 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI KAROLY, HOLLIS C · 2021 to 2025
$1.1M
NIAAA NIH HHS K23 AA028238
6 · The paper itself

Abstract

backgroundFentanyl test strips (FTS) are a harm reduction tool used by individuals seeking to avoid unintentional fentanyl exposure while consuming other illicit substances (e.g., heroin, cocaine). While evidence speaks to the efficacy and acceptability of FTS, there are currently no standardized instructions for the use of FTS as a drug checking tool, and little is known about potential variability across instructions.

methodsWe sought to investigate variability in content across FTS instructions (N = 16) through conducting a thematic content analysis of instructions listed in the first three pages of a Google search. The search was conducted in May of 2024, with "fentanyl test strip instructions" entered as the search term. To be included in the present analysis, the information listed in the search result must have contained explicit instructions for how to use FTS and have been printed in English.

resultsThematic content analysis of FTS instructions yielded 26 codes and 4 themes. Themes included (1) Information about FTS (2) Testing Methods (3) Test Results and (4) Additional Resources. Overall, results indicated considerable variability across the 16 instructions examined, with the greatest variability observed within the testing methods theme.

conclusionInconsistencies in online FTS instructions, such as those identified in the current study, could lead to distrust among people who use drugs and disengagement with this drug checking practice. Standardized and accessible instructions are critical to optimizing the efficacy of FTS as a harm reduction tool and reducing accidental fentanyl exposure.

Indexed as

FentanylOpioid-Related DisordersProduct LabelingReagent StripsSubstance Abuse DetectionEnzyme Multiplied Immunoassay TechniqueHarm ReductionHumansFentanylReagent StripsDrug checkingFentanyl test strip instructionsFentanyl test stripsHarm reductionPublic health communication

Identifiers

PMID40551121
PMCPMC12186409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.