ReviewJournal of cardiovascular translational research2025
Circulating Extracellular Vesicles Predict Complications after Cardiac Surgery.
Review in Journal of cardiovascular translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Extracellular Vesicles as Mediators of Endothelial and Tubular Injury in Cardiac Surgery-Associated Acute Kidney Injury.Biomedicines · 2026Review
- Role of Circulating Microparticles in Impairing Endothelial Function and Activating Oxidative Stress Is Related to No-Reflow in STEMI.Cardiovascular therapeutics · 2026Article
- Biomarkers of perioperative neurocognitive disorders after cardiac surgery: from mechanistic insights to clinical translation.Frontiers in neuroscience · 2026Review
- Extracellular vesicles in cardiac surgery: unlocking new frontiers in cardioprotection and patient outcomes.Clinical and experimental medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Cardiac surgery with cardiopulmonary bypass (CPB) may lead to many postoperative complications. However, many complications cannot be predicted in time using the current clinical methods, or the prediction is not sufficiently accurate, resulting in a delay in treatment. Extracellular vesicles (EVs) are a group of membrane vesicles generated from various sources, including endothelial cells and platelets, upon activation or apoptosis. Here, we summarize the role of circulating EVs in predicting complications after cardiac surgery with cardiopulmonary bypass. We found that EV levels can predict acute heart failure. EV subtypes can predict acute heart failure, acute kidney injury, acute lung injury, blood transfusion, and neurological complications. The components of EVs can predict acute heart failure, acute kidney injury, acute lung injury, and neurological complications. The size distribution of EVs can predict acute lung injury. Therefore, circulating EVs can be used to predict complications after cardiac surgery with cardiopulmonary bypass.
Indexed as
Identifiers
40551060What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.