Evidence map›Paper›PMID 40551027›Full record

ArticleSurgical endoscopy2025

Global insights: fluorescence guided surgery.

Rene Aleman, Julio Aleman, Nicolas Brozzi, Alberto Rancati, Diego Sinagra, Ana Carrasquilla, Raul J Rosenthal, Fernando Dip

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rene AlemanDepartment of General Surgery, Hospital de Clinicas Jose de San Martin, University of Buenos Aires, Ave. Cordoba 2351, C1121ABJ, CABA, Buenos Aires, Argentina. alemanr2@ccf.org.ORCID http://orcid.org/0000-0002-5571-2262
Julio AlemanDepartment of General Surgery, Hospital Herrera-Llerandi, Ciudad de Guatemala, Guatemala.
Nicolas BrozziDepartment of General Surgery, Cleveland Clinic Florida, Weston, FL, USA.
Alberto RancatiDepartment of General Surgery, Hospital de Clinicas Jose de San Martin, University of Buenos Aires, Ave. Cordoba 2351, C1121ABJ, CABA, Buenos Aires, Argentina.
Diego SinagraDepartment of General Surgery, Hospital de Clinicas Jose de San Martin, University of Buenos Aires, Ave. Cordoba 2351, C1121ABJ, CABA, Buenos Aires, Argentina.
Ana CarrasquillaDepartment of General Surgery, Hospital CIMA, San Jose, Costa Rica.
Raul J RosenthalDepartment of General Surgery, Hospital de Clinicas Jose de San Martin, University of Buenos Aires, Ave. Cordoba 2351, C1121ABJ, CABA, Buenos Aires, Argentina.
Fernando DipDepartment of General Surgery, Hospital de Clinicas Jose de San Martin, University of Buenos Aires, Ave. Cordoba 2351, C1121ABJ, CABA, Buenos Aires, Argentina. fernandodip@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluorescence guided surgery (FGS) has been progressively and globally adapted by multiple surgical disciplines over the last decade. Determining its reach and rate of expansion as a navigational surgical technique is challenging from traditional surveys. Google-trends (GT) was introduced as an ongoing-developing web-kit providing data on search trends to analyze the general population interest on specific topics. The purpose of this study is to implement GT data as an indicator for the world's interest in FGS.

methodsGT was used to access data for specific medical subject headings (MeSH) terms associated with FGS, from 2019 to 2024. Collected data included interest over time, interest by country/continent, and related queries. Data were represented as search interest relative to the highest point on global charts for a given region and time. A value of 100% was set as peak popularity for searched term (s). Multiple correlation analyzes were performed between MeSH terms and surgical subspecialties.

resultsThe number of worldwide searches related to the MeSH terms indocyanine green (ICG) and fluorescence imaging (FI) have consistently increased over time, from 47 and 64% in 2019, to 88 and 69% by the end of 2024, respectively. America withholds the continent with the highest interest for ICG and FI, followed by Europe and Asia with 50 and 45%, respectively. Correlation analyzes with surgical subspecialties showed a significant positive relationship between the interest over time for ICG and fluorescent imaging when paired with endocrine surgery (p < 0.0001; p < 0.0001), urologic surgery (p = 0.003; p = 0.002), and gynecologic surgery (p < 0.0001; p = 0.005).

conclusionsThe data conveyed by GT complements the outlook of FGS across the world. Implementing these trends alongside healthcare advocacy and patient therapeutic education, FGS can further expand its applications and potentials to practice safe surgery.

Indexed as

Optical ImagingSurgery, Computer-AssistedHumansIndocyanine GreenIndocyanine GreenFluorescent guided surgeryGoogle trendsIndocyanine greenPatient therapeutic education

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.