ArticleReproductive sciences (Thousand Oaks, Calif.)2025
Psychological Factors Contributing to Health-Related Quality of Life Following Endometriosis Surgery: Results of a Cross-Sectional Study.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Patient-Centred Perspectives on Diagnostic Strategies for Endometriosis: A Qualitative Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
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6 authors.
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Abstract
introductionEndometriosis causes severe and chronic pain leading to impaired Health-Related Quality of Life (HRQoL). While endometriosis surgery does improve pain intensity, psychological factors have an important role in pain perception. The current study aims to evaluate the independent contribution of pain catastrophizing and anxiety and depression to HRQoL between six months and nine years following endometriosis surgery.
methodsThis is a cross-sectional questionnaire study including women with endometriosis who were surgically treated for endometriosis-related pain. Hierarchical multiple linear regression analysis was used to evaluate the relationship of pain catastrophizing and a total score for anxiety and depression to HRQoL, in addition to the contributions of pain intensity, fatigue and sleep quality. In a sub-analysis, we evaluated this relationship in patients with a shorter and with a longer time since surgery (TSS).
resultsThe study included 195 participants, revealing significant correlations between HRQoL, pain catastrophizing and anxiety and depression. Subgroup analysis demonstrated that both pain catastrophizing and a combined anxiety and depression score significantly predicted HRQoL in both the shorter and longer TSS groups. These associations were found in addition to the contribution of pain intensity, fatigue and sleep quality to HRQoL.
conclusionThe current study demonstrates that pain catastrophizing and a combination of anxiety and depression contribute to HRQoL in patients six months to nine years after surgical treatment of endometriosis. Extended post-surgical care could be warranted to address these factors accordingly, for example with psychological care, in addition to surgery alone.
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