Evidence map›Paper›PMID 40550972›Full record

SynthesisCurrent urology reports2025

Comparison of Robot-Assisted Versus Open Partial Nephrectomy for Treating Renal Malignancies With An Emphasis on Oncological Outcomes: A Systematic Review and Meta-Analysis of The Literature.

Diomidis Kozyrakis, Chara Tzavara, Christos Damaskos, Anastasios Zarkadas, Dimitrios Bozios, Athanasios Karmogiannis, Vasileios Konstantinopoulos, Georgios Haronis, Anna-Maria Konomi, Georgios Kallinikas and 6 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Current urology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Diomidis KozyrakisDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece. dkozirakis@yahoo.gr.ORCID https://orcid.org/0000-0003-1236-4381
Chara TzavaraDepartment of Biostatistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Christos DamaskosHellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Anastasios ZarkadasDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Dimitrios BoziosDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Athanasios KarmogiannisDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Vasileios KonstantinopoulosDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Georgios HaronisDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Anna-Maria KonomiDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Georgios KallinikasDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Konstantinos SafioleasDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Athanasios FiliosDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Despoina MytiliniouDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Evangelos RodinosDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Panagiotis FiliosDepartment of Urology, Konstantopouleio-Patision General Hospital of Nea Ionia, Nea Ionia, Athens, Greece.
Dimitrios DimitroulisHellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewRobotic assisted partial nephrectomy (RaPN) is the treatment of choice for small and resectable renal tumors offering better results in terms of blood loss, postoperative complications and length of hospital stay compared with the open partial nephrectomy (OPN), while for both techniques the risk of postoperative renal dysfunction is limited. However, the oncologic outcomes of the robotic procedure are yet to be determined. Therefore, a comprehensive research of PubMed/Medline, Embase and Scopus databases from the year 2000 till June 2024 was performed to elucidate the results related to oncologic outcomes. The ROBINS-I tool for non-randomized cohort studies was applied for the assessment of the quality of the included studies. All statistical analyses were performed with the use of STATA software version 15.0. RECENT

findingsThe study was registered in International Platform of Registered Systematic Review and Metaanalysis Protocols database with the registration number INPLASY202450054. Overall 11 studies with 4758 patients were included in the present systematic review and meta-analysis. No statistically significant difference between the two treatment methods was reconded for the outcomes of overall survival [HR: 1.23 (95% CI: 0.68, 2.20)- p = 0.488], disease-specific survival [OR: 2.53 (95% CI: 0.65, 9.78)- p = 0.179], progression-free survival [HR: 1.04 (95% CI: 0.60, 1.79)- p = 0.901], recurrence-free survival [HR: 0.83 (95% CI = 0.54, 1.27)-p = 0.394] and disease-free survival [OR: 1.01 (95% CI = 0.98, 1.03)-p = 0.582]. The quality of most of the included studies was deemed moderate. Despite the need for more high quality comparative studies it is assumed that these results could be helpful in decision making and in counselling patients with resectable renal tumors to whom a nephron sparing surgery may be considered.

Indexed as

Kidney NeoplasmsNephrectomyRobotic Surgical ProceduresHumansTreatment OutcomeOncologic outcomesPartial nephrectomyRenal tumorsRobot-assistedSurvival

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.