Evidence map›Paper›PMID 40550852›Full record

ArticleCardiovascular and interventional radiology2025

Prospective Registry Study on Thermal Liver Ablation of Primary and Secondary Liver Tumours Named the A-IMAGIO Study.

A L van der Velden, C A M Verhagen, F Gholamiankhah, H Rahmani, R M van Dam, J J van Duijn-de Vreugd, S R Simon, P Hendriks, G C M van Erp, R R M M Knapen and 20 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06179602 (Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors Within the IMAGIO Project), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06179602 recruitingnot on this map

Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors Within the IMAGIO Project (A-IMAGIO)

TypeobservationalSponsorLeiden University Medical CenterRan2024 to 2028Enrolled1,500ConditionsLiver Cancer, Liver Metastases, Liver Metastasis Colon Cancer, Hepatocellular Carcinoma
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

A L van der Velden *Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands. lisa.van.der.velden@mumc.nl.ORCID http://orcid.org/0000-0003-0351-2581
C A M Verhagen *Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
F Gholamiankhah *Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
H Rahmani *Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.
R M van DamGROW, School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.
J J van Duijn-de VreugdDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
S R SimonDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.
P HendriksDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
G C M van ErpDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
R R M M KnapenDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.
L VolmerDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.
K OverduinDepartment of Radiology, Radboud University Medical Center, Nijmegen, The Netherlands.
J P B M BraakDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
R BaleDepartment of Radiology, Medical University Innsbruck, Innsbruck, Austria.
G LaimerDepartment of Radiology, Medical University Innsbruck, Innsbruck, Austria.
R LanocitaDepartment of Radiology, Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
M R MeijerinkDepartment of Radiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Y KampferInstitute for Health Economics and Clinical Epidemiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Gleueler Straße 176-178, 50935, Cologne, Germany.
A DenysDepartment of Radiology and Interventional Radiology, CHUV University of Lausanne, Rue du Bugnon, Lausanne, Switzerland.
P LittlerDepartments of Interventional Radiology, Freeman Hospital, Newcastle Upon Tyne, UK.
B SternbergDepartments of Interventional Radiology, Freeman Hospital, Newcastle Upon Tyne, UK.
H KobeiterRadiology Department, H. Mondor Hospital, Assistance Publique-Hôpitaux de Paris, University Paris Est Creteil, Creteil, France.
M L J SmitsDepartment of Radiology and Nuclear Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands.
M J L van StrijenDepartment of Radiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
K J PietermanDepartment of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.
A BroersenDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
J DijkstraDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
R BrecheisenDepartment of Surgery, Maastricht University Medical Center+, Maastricht, Netherlands.
M C Burgmans *Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
C van der Leij *Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.

Funding

Innovative Health Initiative 101112053
6 · The paper itself

Abstract

purposeThe long-term objective of the Ablation-IMaging and Advanced Guidance for workflow optimization in Interventional Oncology (A-IMAGIO) project is to develop a standardized, accessible, low-complex, high-precision, end-to-end solution for treatment planning, needle guidance, and treatment evaluation for thermal liver ablation. MATERIALS AND

methodsThis is a prospective, international, multicentre, observational registry study. Patients will be included with age ≥ 18 years, diagnosed with primary or secondary liver tumours, and undergoing thermal liver ablation. A detailed dataset of medical history, baseline clinical and imaging parameters, tumour characteristics, ablation technique/parameters, treatment outcomes, periprocedural images, and adverse events, will be collected for all participants. This data will be used to develop AI algorithms for prognostic modelling and quantitative imaging analysis. Additionally, costs associated with thermal liver ablation clinical pathway will be evaluated. EXPECTED GAIN OF KNOWLEDGE: The results of this registry study are expected to provide profound insight in current variability among centres in performing thermal liver ablation, and identify best practices in order to eventually facilitate standardization and universally excellent clinical outcomes.

trial registrationNational Institute of Health Clinical trial database (NCT06179602) https://clinicaltrials.gov/study/NCT06179602 .

Indexed as

Ablation TechniquesLiver NeoplasmsFemaleHumansLiverMaleMiddle AgedProspective StudiesRegistriesArtificial intelligenceColorectal liver metastasesDeep learningHepatocellular carcinomaMicrowave ablationRadiofrequency ablationThermal ablation

Identifiers

PMID40550852
PMCPMC12325461

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.