Evidence map›Paper›PMID 40550832›Full record

ReviewTranslational psychiatry2025

Transdiagnostic neuromodulation of impulsivity: current status and future trajectories.

Gangliang Zhong, Tianzhen Chen, Na Zhong, Tara Rezapour, Abbas Haghparast, Haifeng Jiang, Hang Su, Tifei Yuan, Trevor William Robbins, Jiang Du and 1 more

Abstract readReview
In one paragraph

Review in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Review
  6. Article
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  9. Review
  10. Article
  11. Association of self-stigma, impulsivity, and insomnia with anxiety and depression in patients with Kallmann syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gangliang ZhongShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-1131-4489
Tianzhen ChenShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Na ZhongShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tara RezapourCognitive Psychology Department, Institute for Cognitive Science Studies, Tehran, Iran.
Abbas HaghparastNeuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Haifeng JiangShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hang SuShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tifei YuanShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-0510-715X
Trevor William RobbinsInstitute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China. twr2@cam.ac.uk.ORCID http://orcid.org/0000-0003-0642-5977
Jiang DuShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. dujiangdou@163.com.ORCID http://orcid.org/0000-0002-3644-4581
Min ZhaoShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. drminzhao@smhc.org.cn.ORCID http://orcid.org/0000-0001-8382-3050

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impulsivity, increasingly perceived as a transdiagnostic characteristic, significantly influences diverse psychiatric conditions and emanates beyond the boundaries defined by traditional classification systems. Transdiagnostic research has shed light on the complex clinical manifestations of impulsivity, and the underpinning neural circuitry. The pressing challenge now is to translate this enhanced understanding into precise and potent interventions tailored to these different aspects of impulsivity. Recent advancements in neuromodulation, specifically targeting brain circuits, have provided encouraging evidence for improvements in clinical symptoms, and neural circuitry across various psychiatric conditions, signposting a transformative phase in crafting interventions that tackle impulsivity from a transdiagnostic perspective. However, the field continues to ascertain a universally embraced framework that effectively amalgamates these discoveries into a unified clinical methodology. The Research Domain Criteria (RDoC) delivers a neuroscientifically informed framework that aims to reconcile the neurobiological underpinnings with clinical symptoms, thereby facilitating targeted neuromodulation strategies. In this context, we propose a pioneering RDoC-compliant framework that strategically targets the neural circuits implicated in clinical impulsivity symptoms, applicable across diagnostic categories. Furthermore, we introduce a set of meticulously selected tools for each stage within this framework, thus reinforcing its applicability and aiding future investigative pursuits in this area.

Indexed as

BrainImpulsive BehaviorMental DisordersHumans

Identifiers

PMID40550832
PMCPMC12185744

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.