Evidence map›Paper›PMID 40550716›Full record

ArticleBMJ open2025

Annual cases of colon cancer by age group after Medicaid expansion in the USA in 2014: a difference-in-differences study.

Edgar Asiimwe, Folasade May, Eran Bendavid

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Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Edgar AsiimweDivision of General Internal Medicine, UCSF, San Francisco, California, USA edgar.asiimwe@ucsf.edu.ORCID http://orcid.org/0009-0001-7617-0677
Folasade MayDepartment of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Eran BendavidPrimary Care and Population Health, Department of Medicine, Stanford University, Palo Alto, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies examining the association between Medicaid expansion (ME) under the Affordable Care Act (ACA) and colon cancer incidence have produced mixed results.

objectiveTo re-visit the association between the ACA-ME and annual cases of colon cancer.

designDifference-in-differences (DiD).

settingThe primary analyses used data from the National Cancer Database from 2010 to 2018, a hospital-based cancer registry in the USA. We also conducted exploratory analyses using data from the Surveillance, Epidemiology and End Results (SEER) registry. PATIENTS: Patients aged 40 and older with newly diagnosed colon cancer. MEASUREMENTS: The primary outcome was the percent change in colon cancer of all stages. Secondary outcomes were percent changes in stage I and stage IV cases.

resultsAmong those aged 40-49, we observed a statistically significant greater increase in stage I colon cancer in expansion states relative to non-expansion states (DiD (percent change) 9.7% (95% CI, 2.5% to 17.4%)). In those aged 50-64, we did not observe statistically significant differences between the two state groups in any of the outcomes. Among those aged 65+, we observed a statistically significant relative decrease for all stages in ACA-ME states (-1.0% (95% CI, -1.0% to -3.0%)) and for stage IV (-3.0% (95% CI, -2.0% to -5.0%)). We explored our findings among younger individuals (<50) in trend plots comparing annual colorectal cancer cases to percent uninsured using SEER data and observed that increases in cases coincided with declining uninsurance in several states.

conclusionPost-ME, we observed a greater relative increase in colon cancer among those <50 in expansion states. Our exploratory analyses suggest that fewer barriers to healthcare post-ME may have contributed to these findings; additional studies are needed. We also observed relative decreases in the 65+ age group, corroborating previous reports of spillover benefits in expansion states.

Indexed as

Colonic NeoplasmsMedicaidPatient Protection and Affordable Care ActAdultAgedAge FactorsFemaleHumansIncidenceInsurance CoverageMaleMiddle AgedSEER ProgramUnited StatesGASTROENTEROLOGYHealth policyMass Screening

Identifiers

PMID40550716
PMCPMC12186053

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