ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2026
Detecting cancer recurrence in general practice: a Danish national cohort study.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Breast cancer recurrence: socioeconomic position and general practice involvement - a nationwide cohort study in Denmark.Scandinavian journal of primary health care · 2026Article
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7 authors.
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Abstract
backgroundGPs may detect cancer recurrences between specialised visits or after completed follow-up. There is limited evidence on diagnostic routes to detecting cancer recurrence.
aimTo examine the level of GP involvement in cancer recurrence detection and to assess the time from the index consultation in general practice to a cancer recurrence diagnosis (diagnostic interval). DESIGN AND
settingThis was a retrospective cohort study linking survey data from 667 Danish general practices with national register data.
methodPatients with a recurrence of seven cancer types diagnosed between 1 January 2022 and 31 May 2024 were included. The patients' GPs provided details on how the recurrence was detected.
resultsThe GP survey achieved a response rate of 1265/2611 (48%). Of 1081 patients with recurrence, 478 (44%) first presented signs or symptoms of recurrence in general practice. Recurrence was diagnosed in 758 patients (70%) while they were under active specialised follow-up, and in 291 patients (27%) after completion of follow-up. Of 352 patients with a symptomatic presentation in general practice, the diagnostic pathway was initiated in general practice in 243 (69%), during subsequent follow-up in 57 (16%), and via other routes in 52 (15%). For patients with general practice-initiated diagnostic pathways, the 50th and 90th percentile of the diagnostic interval was 48 and 251 days for symptomatic presentations and 23 and 125 days for asymptomatic presentations, respectively.
conclusionFour in 10 patients with cancer recurrence had their first point of contact in general practice. However, significant delays were observed. Improving detection pathways for cancer recurrence in general practice may benefit survivors across cancer types.
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