Evidence map›Paper›PMID 40549978›Full record

ArticleJournal of chemical information and modeling2025

CHARMM-GUI

Seonghan Kim, Nathan R Kern, Lauren Paolucci, Alan Jaemin Jo, Christopher P Baryiames, D Peter Tieleman, Linda Columbus, Wonpil Im

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seonghan KimDepartment of Bioengineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.
Nathan R KernDepartment of Computer Science & Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.ORCID 0000-0003-0936-7274
Lauren PaolucciDepartment of Bioengineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.
Alan Jaemin JoWilliam Howard Taft Charter High School, Woodland Hills, California 91364, United States.
Christopher P BaryiamesDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
D Peter TielemanDepartment of Biological Sciences and Centre for Molecular Simulation, University of Calgary, Calgary, Alberta T2N 1N4, Canada.ORCID 0000-0001-5507-0688
Linda ColumbusDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID 0000-0002-2574-0561
Wonpil ImDepartment of Bioengineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.ORCID 0000-0001-5642-6041

Funding

Development of Computational Tools and Their Applications to Various Biological SystemsR35GM153458 · NIGMS · LEHIGH UNIVERSITY · PI Wonpil Im · 2024 to 2026
$1.2M
NIGMS NIH HHS R35 GM153458
6 · The paper itself

Abstract

Membrane mimetics, such as detergent micelles, nanodiscs, and amphipol complexes, which can provide membrane-like environments while retaining small and soluble features, have been utilized to study membrane proteins. A bicelle, composed of varying lipids and detergents, is a useful membrane mimetic because the lipid-to-detergent ratio, the

Indexed as

Lipid BilayersSoftwareDetergentsDimyristoylphosphatidylcholineMicellesModels, MolecularMolecular Dynamics SimulationUser-Computer InterfaceDetergentsDimyristoylphosphatidylcholineLipid BilayersMicelles

Identifiers

PMID40549978
PMCPMC12264929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.