Evidence map›Paper›PMID 40549917›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

JunB-HBZ nuclear translocation by TGF-β is a key driver in HTLV-1-mediated leukemogenesis.

Wenyi Zhang, Takafumi Shichijo, Xueda Chen, Miho Watanabe, Kisato Nosaka, Masao Matsuoka, Jun-Ichirou Yasunaga

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. JunB-HBZ nuclear translocation by TGF-β is a key driver in HTLV-1-mediated leukemogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenyi ZhangDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0009-0006-9885-411X
Takafumi ShichijoDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Xueda ChenDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-4962-8320
Miho WatanabeDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0009-0002-0764-2287
Kisato NosakaDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0001-6682-2451
Masao MatsuokaDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-0473-754X
Jun-Ichirou YasunagaDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-7939-2080

Funding

Japan Agency for Medical Research and Development (AMED) 20cm0106306h0005Japan Agency for Medical Research and Development (AMED) 20fk0108088h0002Japan Agency for Medical Research and Development (AMED) 21am0401003h0003Japan Agency for Medical Research and Development (AMED) 24fk0108629h0003MEXT | Japan Society for the Promotion of Science (JSPS) 19H03689MEXT | Japan Society for the Promotion of Science (JSPS) 23H02936MEXT | Japan Society for the Promotion of Science (JSPS) 23K15303MEXT | Japan Society for the Promotion of Science (JSPS) 24K22136MEXT | Japan Society for the Promotion of Science (JSPS) 25K11650MEXT | Japan Society for the Promotion of Science (JSPS) 25K19580
6 · The paper itself

Abstract

The

Indexed as

Basic-Leucine Zipper Transcription FactorsHuman T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellRetroviridae ProteinsTranscription FactorsTransforming Growth Factor betaActive Transport, Cell NucleusAnimalsCarcinogenesisCell NucleusCell ProliferationHumansMiceSmad3 ProteinBasic-Leucine Zipper Transcription FactorsHBZ protein, human T-cell leukemia virus type IJunB protein, humanRetroviridae ProteinsSmad3 ProteinSMAD3 protein, humanTranscription FactorsTransforming Growth Factor betaATLHBZHTLV-1JunBTGF-β/Smad signaling pathway

Identifiers

PMID40549917
PMCPMC12232710

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.