Evidence map›Paper›PMID 40549903›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Immune cell profiling reveals diverse niches of immune residents of the enteric nervous system and potential neuroimmune interactions.

Haozhe Wang, Aidil Zaini, Bailey Cardwell, Matthew C Rowe, Alana Butler, Connie H Y Wong, Daniel P Poole, Benjamin Marsland, Joel C Bornstein, Nicola L Harris

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Intestinal muscularis in health and disease.Communications biology · 2026
    Review
  2. Letter to the Editor: Deciphering macrophage heterogeneity and optimizing probioticsWorld journal of gastrointestinal pharmacology and therapeutics · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haozhe Wang *Department of Immunology, School of Translational Medicine, Monash University, Melbourne 3004, VIC, Australia.
Aidil Zaini *Department of Immunology, School of Translational Medicine, Monash University, Melbourne 3004, VIC, Australia.
Bailey CardwellDepartment of Immunology, School of Translational Medicine, Monash University, Melbourne 3004, VIC, Australia.ORCID 0000-0003-4686-4210
Matthew C RoweDrug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.ORCID 0009-0006-6357-2972
Alana ButlerDepartment of Immunology, School of Translational Medicine, Monash University, Melbourne 3004, VIC, Australia.
Connie H Y WongCentre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash Medical Centre Monash University, Clayton 3168, VIC, Australia.ORCID 0000-0002-9020-1847
Daniel P PooleDrug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.ORCID 0000-0002-6168-8422
Benjamin MarslandDepartment of Immunology, School of Translational Medicine, Monash University, Melbourne 3004, VIC, Australia.
Joel C BornsteinDepartment of Anatomy and Physiology, University of Melbourne, Melbourne 3010, VIC, Australia.ORCID 0000-0002-7518-7717
Nicola L HarrisDepartment of Immunology, School of Translational Medicine, Monash University, Melbourne 3004, VIC, Australia.ORCID 0000-0003-2922-0210

Funding

Federal Government | DHAC | National Health and Medical Research Council (NHMRC) SRF-B
6 · The paper itself

Abstract

Gastrointestinal (GI) neuroimmune interactions are crucial sensors and regulators of tissue homeostasis. Most enteric neurons reside within the myenteric plexus of the enteric nervous system in the muscular region, forming a structure called the

Indexed as

Enteric Nervous SystemNeuroimmunomodulationAnimalsGastrointestinal TractMacrophagesMiceMyenteric PlexusNeuronsSingle-Cell Analysisenteric nervous systemgastrointestinal tractGI homeostasisneuroimmune interactions

Identifiers

PMID40549903
PMCPMC12232633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.