Evidence map›Paper›PMID 40549768›Full record

ArticlePloS one2025

Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021.

Lixia Lin, Yongshun Liang, Guiyang Jiang, Qingqiao Gan, Tianqi Yang, Peipei Liao, Hao Liang

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Equity in Uptake of NHS and Private Optometry Services in Wales by Age and Gender.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Loss of Peroxiredoxin 6 Drives Age-Related Klf9/NF-Antioxidants (Basel, Switzerland) · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Complexity and Barriers to Vision Care: A Narrative Review Informed by a Mobile Eye Program.International journal of environmental research and public health · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lixia LinOphthalmology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, GuangXi, China.
Yongshun LiangOphthalmology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, GuangXi, China.
Guiyang JiangRehabilitation Medicine Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Qingqiao GanOphthalmology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, GuangXi, China.
Tianqi YangOphthalmology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, GuangXi, China.
Peipei LiaoOphthalmology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, GuangXi, China.
Hao LiangOphthalmology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, GuangXi, China.ORCID 0000-0002-8239-6728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCataract is the most prevalent cause of blindness. Surgery remains the only effective and widely accepted treatment; early diagnosis and intervention can significantly prevent blindness. Hence,Understanding the current epidemiological status of cataract is crucial for formulating better healthcare policies and effectively preventing blindness due to cataract.

designThis study utilizes Global burden of Disease (GBD) 2021 data to conduct an in-depth analysis of the burden of cataract from 1990 to 2021, including gender disparities, risk factors, and the relationship between Socio-Demographic index (SDI) and disease burden. Additionally, we performed a frontier analysis of Disability-Adjusted Life Years (DALYs) due to cataract from 1990 to 2021. Finally, we used the BAPC model to project the burden of cataract by gender from 2022 to 2030.

resultsThe study revealed that the global burden of cataract remains significant. Worldwide, the Estimate Annual Percentage Change (EAPC) for cataract prevalence was 0.2117([95% CI] 0.1172-0.3063); the EAPC for cataract DALYs is -0.4798([95%CI] -0.5766--0.3828). Predominantly affecting females, individuals aged 50 and older, and those in medium-low and low SDI regions. Furthermore, the Bayesian Age-Period-Cohort (BAPC) model forecast a gradual decline in the global burden of cataract over the next nine years.

conclusionThis study utilized GBD 2021 to provide an in-depth analysis of the current global disease burden of cataracts. The results showed that although the Age-Standardized Rate (ASR) of DALYs decreased, the overall cataract Number still showed an increasing trend from 1990 to 2021 and 2022-2030.

Indexed as

CataractGlobal Burden of DiseaseAdolescentAdultAgedAged, 80 and overBlindnessDisability-Adjusted Life YearsFemaleGlobal HealthHumansMaleMiddle AgedPrevalenceQuality-Adjusted Life YearsRisk Factors

Identifiers

PMID40549768
PMCPMC12185006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.