Evidence map›Paper›PMID 40549763›Full record

ArticlePLOS global public health2025

Sex differences in severe acute malnutrition in children under 5 years in Zambia.

Gift C Chama, Situmbeko Liweleya, Lweendo Muchaili, Bislom C Mweene, Sydney Mulamfu, Lukundo Siame, Sepiso K Masenga

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gift C ChamaDepartment of Physiological Sciences, Mulungushi University, School of Medicine and Health Sciences, Livingstone, Zambia.ORCID https://orcid.org/0009-0004-4161-1876
Situmbeko LiweleyaDepartment of Physiological Sciences, Mulungushi University, School of Medicine and Health Sciences, Livingstone, Zambia.
Lweendo MuchailiDepartment of Physiological Sciences, Mulungushi University, School of Medicine and Health Sciences, Livingstone, Zambia.
Bislom C MweeneDepartment of Physiological Sciences, Mulungushi University, School of Medicine and Health Sciences, Livingstone, Zambia.
Sydney MulamfuDepartment of Physiological Sciences, Mulungushi University, School of Medicine and Health Sciences, Livingstone, Zambia.
Lukundo SiameDepartment of Physiological Sciences, Mulungushi University, School of Medicine and Health Sciences, Livingstone, Zambia.ORCID https://orcid.org/0009-0002-4810-7352
Sepiso K MasengaDepartment of Physiological Sciences, Mulungushi University, School of Medicine and Health Sciences, Livingstone, Zambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute malnutrition (SAM) is a critical public health issue, particularly in low and middle-income countries like Zambia, where it significantly contributes to under-five mortality. While general factors associated with SAM, including its overall burden, are well documented, the role of sex differences in correlates of SAM has not been thoroughly explored. Hence, this study aimed to examine sex differences in correlates of SAM by identifying key factors influencing malnutrition in males and females under five years, with particular attention to comorbid conditions such as Human Immunodeficiency Virus (HIV) and Tuberculosis (TB), which are known to complicate malnutrition in this population. We conducted a retrospective cross-sectional study utilizing data from 429 medical records of children aged 6 months to 5 years who were attended to at Livingstone University Teaching Hospital between 2020 and 2022. The median age at diagnosis for both males and females was 18 months, with interquartile ranges of 11-25 months and 12-24 months, respectively. Females had a higher prevalence of SAM (24.3%, n = 46) compared to males (19.58%, n = 47). TB was significantly associated with SAM in both males (AOR: 14.30, 95% CI: 2.08-98.5, p = 0.006) and females (AOR: 40.50, 95% CI: 4.83-340, p < 0.001), and the lymphocyte-to-monocyte ratio was also associated with SAM in males (AOR: 1.39, 95% CI: 1.05-1.83, p = 0.017) and females (AOR: 1.22, 95% CI: 1.00-1.49, p = 0.045). Additionally, comorbidities (AOR: 4.1, 95% CI: 1.13-14.90, p = 0.031) and age (AOR: 0.91, 95% CI: 0.85-0.97, p = 0.009) were associated with SAM in females, while these associations were not significant in males. Overall, females are more frequently diagnosed with SAM, most likely due to the presence of comorbidities such as TB and HIV. TB was found to be a critical risk factor for SAM in both sexes, highlighting the need for sex-specific interventions in the management of SAM.

Identifiers

PMID40549763
PMCPMC12184909

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.