Evidence map›Paper›PMID 40549693›Full record

SynthesisPloS one2025

Recruitment and retention strategies for improving representation in clinical research: A meta-synthesis.

Carson J Peters, Joan M Greve, Arvin Karbasi, Michelle Walker, Luyi Adesanya, Joyonna Gamble-George, Nicole Redmond, Brenda Adjei, Olufunmilola Olufemi

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Navigating Long-Term Co-Creative Research With Young Adults Diagnosed With Cancer: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carson J PetersDepartment of Behavioral and Community Health, School of Public Health, University of Maryland, College Park, Maryland, United States of America.
Joan M GreveSmall Business Innovation Research Development Center, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Arvin KarbasiSchool of Medicine, Stanford University, Stanford, California, United States of America.ORCID 0000-0001-6096-9647
Michelle WalkerDepartment of Health Policy and Management, School of Public Health, University of Maryland, College Park, Maryland, United States of America.
Luyi AdesanyaSchool of Public Health, Loma Linda University, Loma Linda, California, United States of America.
Joyonna Gamble-GeorgeCollege of Nursing, New York University, New York, New York, United States of America.ORCID 0000-0002-5492-9216
Nicole RedmondDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Brenda AdjeiOffice of the Associate Director of the Healthcare Delivery Research Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Olufunmilola OlufemiOffice of Technology Transfer, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America.ORCID 0009-0004-4105-7481

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify innovative strategies that may increase recruitment and/or retention of groups less represented in chronic disease clinical research.

methodsA systematic review was conducted. Inclusion criteria were: (a) NIH-defined racial and ethnic minority groups and clinical research; (b) evidence-based, clinical research recruitment and/or retention strategies involving the leading causes of mortality and morbidity in the United States; (c) conducted in the United States; and (d) qualitative design. Data exploring the strategies were extracted and thematically analyzed.

resultsTwenty-seven studies were included. Studies focused on cancer (70%), recruitment (93%), and perspectives from clinicians (63%). The most referenced strategies were education (44%), communication (48%), and community-based participatory research (63%). Critical themes include empowerment, transparency, trust, and sustainability.

conclusionsStrategies must prioritize the community and be implemented sustainably, where cultural humility and community-based participatory research are foundational.

Indexed as

Biomedical ResearchPatient SelectionCommunity-Based Participatory ResearchHumansMinority GroupsUnited States

Identifiers

PMID40549693
PMCPMC12184919

What OpenQuestion holds

Textmetadata
LicenceCC0
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.