Evidence map›Paper›PMID 40549559›Full record

ArticleeLife2025

The geometry and dimensionality of brain-wide activity.

Zezhen Wang, Weihao Mai, Yuming Chai, Kexin Qi, Hongtai Ren, Chen Shen, Shiwu Zhang, Guodong Tan, Yu Hu, Quan Wen

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Persistent selection on size explains micro- and macroevolutionary alignments in fly wings.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zezhen Wang *School of Data Science, University of Science and Technology of China, Hefei, China.ORCID https://orcid.org/0009-0006-1401-9871
Weihao Mai *Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.ORCID https://orcid.org/0000-0002-2320-2276
Yuming Chai *Hefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, University of Science and Technology of China, Hefei, China.ORCID https://orcid.org/0000-0003-0184-1824
Kexin QiHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, University of Science and Technology of China, Hefei, China.
Hongtai RenDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China.
Chen ShenHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, University of Science and Technology of China, Hefei, China.
Shiwu ZhangDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China.
Guodong TanDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Yu HuDivision of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.ORCID https://orcid.org/0000-0003-0790-1605
Quan WenSchool of Data Science, University of Science and Technology of China, Hefei, China.ORCID https://orcid.org/0000-0003-0268-8403

Funding

Ministry of Science and Technology of the People's Republic of China 2022ZD0211900National Science Foundation of China NSFC-32071008Research Grants Council, University Grants Committee ECS-26303921
6 · The paper itself

Abstract

Understanding neural activity organization is vital for deciphering brain function. By recording whole-brain calcium activity in larval zebrafish during hunting and spontaneous behaviors, we find that the shape of the neural activity space, described by the neural covariance spectrum, is scale-invariant: a smaller,

Indexed as

BrainNeuronsAnimalsBehavior, AnimalCalciumLarvaMiceZebrafishCalciumdimension reductionEuclidean random matrixfunctional spacemouseneural covariance spectrumneurosciencephysics of living systemsscale invariancewhole-brain imagingzebrafish

Identifiers

PMID40549559
PMCPMC12185106

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.