Evidence map›Paper›PMID 40549439›Full record

ArticleSexually transmitted diseases2025

Correlates of Condom Failure in Men Who Have Sex With Men in Kenya, Malawi, and South Africa: Findings From the HIV Prevention Trials Network 075 Study.

Theo G M Sandfort, Charlotte E Rinnooy Kan, Thomas Corbeil, Victor Mudhune, Erica L Hamilton, Sufia Dadabhai, Caitlin Laughney, Ravindre Panchia, Doerieyah Reynolds

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Theo G M SandfortFrom the HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Department of Psychiatry, Columbia University.ORCID 0000-0002-4986-1739
Charlotte E Rinnooy KanFrom the HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Department of Psychiatry, Columbia University.
Thomas CorbeilMental Health Data Science, New York State Psychiatric Institute, New York, NY.
Victor MudhuneKenya Medical Research Institute, Kisumu Clinical Research Site, Kisumu, Kenya.
Erica L HamiltonNetwork and Collaborative Research Division, FHI 360, Durham, NC.
Sufia DadabhaiKamuzu University of Health Sciences-Johns Hopkins Research Project, Blantyre, Malawi.
Caitlin LaughneyFrom the HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Department of Psychiatry, Columbia University.
Ravindre PanchiaPerinatal HIV Research Unit, University of the Witwatersrand, Soweto HPTN CRS, Soweto.
Doerieyah ReynoldsDesmond Tutu HIV Centre, UCT Medical School, Cape Town, South Africa.

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI MYRON Scott COHEN, Sinead Delany-Moretlwe · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
The Malawi Clinical Trials UnitUM1AI069518 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JACKY M JENNINGS, TAHA E TAHA · 2012 to 2026
$43.8M
INSPIRE : Interdisciplinary Social and Behavioral Science Prevention and Intervention REsearch in HIVT32MH019139 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Claude Ann Mellins, Jae M. Sevelius · 1989 to 2026
$10.8M
In-depth Understanding of HIV Risk Behavior among Men Who Have Sex With Men in Sub-Saharan Africa: Secondary Analysis of HPTN 075 DataR21MH130217 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI SANDFORT, THEODORUS G.M. · 2022 to 2023
$455k
NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619NIAID NIH HHS UM1 AI069518NIMH NIH HHS P30 MH043520NIMH NIH HHS R21 MH130217NIMH NIH HHS T32 MH019139
6 · The paper itself

Abstract

backgroundResearch on condom failure among African men who have sex with men (MSM) is rare; therefore, we sought to identify multilevel correlates of condom failure.

methodsUsing logistic regression, we identified the associations of various participant, partnership, and sexual interaction characteristics with condom slippage and breakage among African MSM participating in HIV Prevention Trials Network (HPTN) 075, a 1-year, multinational, prospective cohort study (2015-2017).

resultsOf 401 participants, 387 (96.5%) reported at least one sexual interaction in which condoms were used. Condom slippage was reported in 194 (10.2%) of the 1908 sexual interactions reported by participants and breakage in 223 (11.7%) interactions. Both slippage and breakage were reported less frequently by participants in ongoing intimate relationships compared with those who were not (odds ratio [OR], 0.52; 95% confidence interval [CI], 0.29-0.95; OR, 0.57; 95% CI, 0.34-0.93). Slippage and breakage occurred more frequently when sex happened under the influence of substances (OR, 1.67; 95% CI, 1.13-2.46; OR, 2.08; 95% CI, 1.48-2.93) or when sex was forced (OR, 3.18; 95% CI, 1.68-6.02; OR, 2.39; 95% CI, 1.41-4.04). Having experienced homophobia was also associated with slippage and breakage (OR, 1.32; 95% CI, 1.04-1.68; OR, 1.35; 95% CI, 1.10-1.65).

conclusionsOngoing condom failures suggest the importance of continued condom education of African MSM, addressing circumstances that promote or hinder optimal use, and increasing their control in sexual interactions. Experienced homophobia might as a distal factor also contribute to condom failure.

Indexed as

CondomsEquipment FailureHIV InfectionsHomosexuality, MaleAdolescentAdultHumansKenyaMalawiMaleProspective StudiesSexual BehaviorSexual PartnersSouth AfricaYoung Adult

Identifiers

PMID40549439
PMCPMC12327758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.