Evidence map›Paper›PMID 40549340›Full record

ArticleJournal of occupational rehabilitation2026

Changes and Determinants of Health-Related Quality of Life in Patients with Work-Related Traumatic Musculoskeletal Injuries: A Longitudinal Analysis of HRQoL and the EQ-VAS.

Ilda Adrovic, Michaela Coenen, Stefan Simmel, Sandra Kus

Abstract readMulticenter Study
In one paragraph

Article in Journal of occupational rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ilda AdrovicInstitute for Medical Information Processing, Biometry, and Epidemiology-IBE, Chair of Public Health and Health Services Research, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Elisabeth-Winterhalter-Weg 6, 81377, Munich, Germany.
Michaela CoenenInstitute for Medical Information Processing, Biometry, and Epidemiology-IBE, Chair of Public Health and Health Services Research, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Elisabeth-Winterhalter-Weg 6, 81377, Munich, Germany.
Stefan SimmelDepartment for Rehabilitation, BG Hospital Murnau, Murnau, Germany.
Sandra KusInstitute for Medical Information Processing, Biometry, and Epidemiology-IBE, Chair of Public Health and Health Services Research, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Elisabeth-Winterhalter-Weg 6, 81377, Munich, Germany. skus@ibe.med.uni-muenchen.de.

Funding

German Social Accident Insurance (DGUV) FR265
6 · The paper itself

Abstract

purposeThis study aims to analyze change over time in health-related quality of life and the current overall health status of patients with severe musculoskeletal injuries, specifically focusing on those who have undergone inpatient rehabilitation following work-related injuries.

methodsData were sourced from the icfPROreha research project (DRKS-ID: DRKS00014857), involving a multicenter longitudinal study conducted across ten German clinics. The study population comprised patients who had sustained severe musculoskeletal work-related injuries. The EuroQol 5 Dimensions 5 Levels (EQ-5D-5L) was used to assess changes in health-related quality of life (HRQoL) measured at admission (t1), discharge (t2), and four follow-up periods up to 78 weeks after discharge. Descriptive analyses were conducted to illustrate the development of HRQoL across all time points. In addition, the current overall health status was measured using the EuroQol Visual Analogue Scale (EQ-VAS) at the same time points. Multilevel growth models were used to analyze change over time in EQ-VAS scores, considering the biopsychosocial perspective of health as indicated by the International Classification of Functioning, Disability, and Health (ICF), developed by the WHO.

resultsIn total, 698 patients [males: 75.2%; mean age 47.5 years (SD ± 12.3)] with severe musculoskeletal work-related injuries were included in the analyses. The mean EQ-VAS at baseline was 50.3 and the mean EQ-5D-5L index was 0.6. Descriptive analyses of the EQ-5D-5L showed significant improvements across all five dimensions of HRQoL after discharge, with the most pronounced changes observed in mobility and usual activities. Moreover, the study demonstrated a significant improvement in the EQ-VAS over time. Baseline EQ-VAS had a substantial influence on subsequent changes, with various factors such as psychological well-being, visible consequences and severity of injury affecting recovery outcomes. Notably, differences in health status over time were observed across different injury types.

conclusionThe study demonstrates significant enhancements in the current overall health status among patients with traumatic musculoskeletal injuries following workplace or commuting accidents during inpatient rehabilitation. Furthermore, these findings emphasize the application of the ICF framework in capturing the multidimensional aspects of patient recovery. Despite improvements, patients' health status did not reach the levels observed in the general population, indicating the need for ongoing support and targeted interventions to ensure long-term recovery.

Indexed as

Health StatusMusculoskeletal DiseasesMusculoskeletal SystemOccupational InjuriesQuality of LifeAdultFemaleGermanyHumansLongitudinal StudiesMaleMiddle AgedSurveys and QuestionnairesBiopsychosocialFractureOccupational accidentPolytraumaQuality of life

Identifiers

PMID40549340
PMCPMC13364787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.