ArticleUpdates in surgery2025
Comparative outcomes of the CoolSeal Reveal in thyroid surgery.
Article in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Energy-based hemostatic devices have been adopted by surgeons to provide durable hemostasis in thyroid operations. The CoolSeal® Reveal is the newest of these devices, and literature regarding its comparative efficacy remains sparse. This study compared surgical outcomes of the CoolSeal® Reveal with well-established hemostatic devices commonly employed in thyroid operations. This was a retrospective review of 1219 patients who underwent thyroid resections by a single surgeon from May 2017 to September 2023. Surgical outcomes for the Harmonic® Ultrasonic Scalpel (n = 645), LigaSure™ Small Jaw (n = 185), and CoolSeal® Reveal (n = 389) were evaluated and rates of postoperative complications and operative times for each device were compared. An overall complication rate of 4.2% (n = 51) was observed with no significant differences across devices (p = .818) in terms of postoperative hematoma (p = .163), recurrent laryngeal nerve injury (p = .217), or postoperative hypocalcemia (p > .999). The CoolSeal® demonstrated a lower median operating time of 51 min (p < .0001) and 80 min (p = .001) for lobectomy and total thyroidectomy, respectively, when compared to the Harmonic®. No differences were observed when comparing the CoolSeal® and LigaSure™. The CoolSeal® Reveal appears to demonstrate outcomes that are comparable to the well-studied and time-tested LigaSure™ and Harmonic® devices. Our early experience with the CoolSeal® found it to be a safe and effective alternative to these devices; however, it needs to be studied in greater numbers to corroborate these results.
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