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ArticleClinical oral investigations2025

Comprehensive 3D measurements of condyle changes in patients with class III asymmetry after bimaxillary orthognathic surgery.

Chi Zhang, Yule Xu, Yuxiang Wei, Yuan Li, Songsong Guo, Hongbing Jiang, Dongmiao Wang, Jie Cheng

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Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Chi ZhangDepartment of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital, Nanjing Medical University, Jiangsu, 210029, China.
Yule XuState Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Jiangsu, 210029, China.
Yuxiang WeiState Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Jiangsu, 210029, China.
Yuan LiDepartment of Orthodontics, The Affiliated Stomatological Hospital, Nanjing Medical University, Jiangsu, 210029, China.
Songsong GuoDepartment of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital, Nanjing Medical University, Jiangsu, 210029, China.
Hongbing JiangDepartment of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital, Nanjing Medical University, Jiangsu, 210029, China.
Dongmiao WangDepartment of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital, Nanjing Medical University, Jiangsu, 210029, China.
Jie ChengDepartment of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital, Nanjing Medical University, Jiangsu, 210029, China. leonardo_cheng@163.com.

Funding

National Natural Science Foundation of China 82072991
6 · The paper itself

Abstract

objectivesThe present study was aimed to assess three-dimensional (3D) quantitative changes of condyle in patients with Class III facial asymmetry after bimaxillary orthognathic surgery. MATERIALS AND

methodsFifty-five eligible patients with Class III facial asymmetry received Le Fort I osteotomy and bilateral sagittal split osteotomy (BSSO) with or without genioplasty from January 2020 to June 2022 were included. Cone-beam computed tomography (CBCT) for each patient was collected at 3 stages: 1 week preoperatively (T0), immediately after surgery (T1) and at least 12 months postoperatively (T2). Positional changes and bone remodeling of condyles were measured based on voxel- and surface-registrations using ITK-SNAP and 3D Slicer and compared between various stages. Correlations between these changes, mandibular surgical movements and skeletal stability were further explored.

resultsMost condyles at deviated side (DS) tended to shift inferiorly, anteriorly and to non-deviated side (NDS), while condyles at NDS were displaced posteriorly, inferiorly and laterally from T0 to T1. Condyles showed upward pitch, outward yaw and lateral roll at both sides. Bone resorption was more frequently observed in the posterior area of condylar surface at NDS. Significant correlations were found between mandibular anteroposterior/transverse stability and DS condylar lateral shift or NDS condylar yawing after surgery (T1-T2), respectively.

conclusionsOur results comprehensively characterize 3D condylar changes and their associations with skeletal stability after surgical correction of Class III facial asymmetry. CLINICAL RELEVANCE: These findings advance current understanding of complex condylar changes after bimaxillary orthognathic surgery in Class III facial asymmetry patients.

Indexed as

Facial AsymmetryImaging, Three-DimensionalMalocclusion, Angle Class IIIMandibular CondyleOrthognathic Surgical ProceduresAdolescentAdultCone-Beam Computed TomographyFemaleGenioplastyHumansMaleOsteotomy, Le FortOsteotomy, Sagittal Split RamusClass III facial asymmetryCondylar remodelingCone-beam computed tomographyOrthognathic surgeryThree-dimensional measurement

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