Evidence map›Paper›PMID 40549180›Full record

ArticleAbdominal radiology (New York)2026

Assessment of the distribution of pancreatic iron deposition in non-transfusion dependent thalassemia.

Chaotian Luo, Fei Peng, Xiaojing Ning, Cheng Tang, Linlin Liang, Mingrui Yang, Yanyan Zhang, Kaiming Guan, Zengqin Liang, Peng Peng

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Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Chaotian LuoDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Fei PengDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xiaojing NingDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Cheng TangDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. tangcheng-2001@126.com.
Linlin LiangDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Mingrui YangDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yanyan ZhangDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Kaiming GuanDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zengqin LiangDepartment of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Peng PengDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. doublep@126.com.

Funding

Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project S2022072Guangxi Zhuang Autonomous Region Health Committee Scientific Research Project Z20200519National Natural Science Foundation of China 81760305Natural Science Foundation of Guangxi Zhuang Autonomous Region, China 2023GXNSFAA026009Open project of the NHC Key Laboratory of Thalassemia Medicine GJWJWDP202208Open project of the NHC Key Laboratory of Thalassemia Medicine GJWJWDP202306The Key Laboratory of Children's Disease Research in Guangxi's Colleges and Universities GXCDR2023001
6 · The paper itself

Abstract

purposeTo assess the homogeneity of pancreatic iron deposition in non-transfusion dependent thalassemia (NTDT).

methodsThe segments (head, body, and tail) R2* of the pancreas were measured separately in 119 cases that underwent pancreatic magnetic resonance imaging multi-echo gradient sequences of NTDT and analyzed the consistency.

resultsThe median R2* values for pancreas: head = 26.7 1/s, body = 26.5 1/s, tail = 24.9 1/s, and the analysis showed no significant differences in pancreatic segments R2* value (P = 0.204). There were no significant difference in pancreatic segments R2* values within the subgroup of sex, heart iron degree, liver iron degree and pancreatic iron degree (all P > 0.05). There is a moderate correlation between the standard deviation and the coefficient of variation of R2* values for each segment of the pancreas and the mean value of the pancreas (r = 0.683, P < 0.001; r = 0.411, P < 0.001), R2* values were no different among pancreatic segments in the extremely severe iron overload group (with three times R2* the pancreatic Oiron overload threshold).

conclusionThere were no significant differences in pancreatic iron deposition among the segments in NTDT, and R2* values for single-segment could be selected to assess the overall iron deposition of the pancreas.

Indexed as

IronIron OverloadMagnetic Resonance ImagingPancreasThalassemiaAdolescentAdultChildFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultIronIron depositionMagnetic resonance imagingMulti-echo gradient sequenceNon-transfusion dependent thalassemiaPancreas

Identifiers

PMID40549180

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