Evidence map›Paper›PMID 40549174›Full record

ArticleEuropean child & adolescent psychiatry2025

ADHD medication dispensing trends in Dutch youth before and after the implementation of the Youth Act (2010-2022).

Lisa T Ringeling, Aarushi Srivastava, Ravish N Gangapersad, Jens H J Bos, Brenda C M de Winter, Eelko Hak, Manon H J Hillegers, Birgit C P Koch, Catharina C M Schuiling-Veninga, Bram Dierckx

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Article in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Lisa T RingelingDepartment of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands. l.ringeling@erasmusmc.nl.ORCID http://orcid.org/0000-0002-9354-6429
Aarushi SrivastavaDepartment of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0009-0002-6603-4986
Ravish N GangapersadDepartment of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0009-0009-8389-2131
Jens H J BosDepartment of Pharmacotherapy, -Epidemiology and -Economics (PTEE), University of Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0001-9209-7564
Brenda C M de WinterDepartment of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-4452-8443
Eelko HakDepartment of Pharmacotherapy, -Epidemiology and -Economics (PTEE), University of Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0003-0849-7210
Manon H J HillegersDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0003-4877-282X
Birgit C P KochDepartment of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-1202-3643
Catharina C M Schuiling-VeningaDepartment of Pharmacotherapy, -Epidemiology and -Economics (PTEE), University of Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0002-8527-2608
Bram DierckxDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-5045-9894

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe Youth Act, implemented by the Dutch government in 2015, aimed to provide more efficient, coherent, and cost-effective care tailored to the specific needs of children, while also reducing medicalization. Between 2003 and 2013, there was a four-fold increase in methylphenidate prescriptions among Dutch children aged 4 to 18 years. However, the impact of the Youth Act on the ADHD medication dispensing remains unassessed. This study investigated changes in ADHD medication dispensing patterns among Dutch youth following the implementation of the Youth Act.

methodA before-after retrospective cohort study was conducted using data from the Dutch community pharmacy-based IADB.nl database among 137,684 youths aged 0-19 years using ADHD medication between 2010 and 2022.

resultsA significant decrease in overall ADHD medication dispensing prevalence rates per thousand youths was observed in 2022 compared to 2015 (35.2 vs. 45.7, p < 0.001). Methylphenidate accounted for approximately 87% of all ADHD medication dispensing. Incidence rates decreased significantly among children aged 7-12 from 2015 to 2022 (9 vs. 7.3, p < 0.001), while incidence rates increased significantly in adolescent youths (4 vs. 4.8, p = 0.008), particularly among adolescent females (3.5 vs. 5.3, p < 0.001). Females had lower prevalence rates and shorter durations of ADHD medication use compared to males, with no difference in daily dose observed.

conclusionADHD medication dispensing among Dutch youth declined following the 2015 implementation of the Youth Act. However, other factors such as the DSM-5 revision, COVID-19, and medication shortages likely contributed to this decrease, suggesting a multifactorial explanation for the observed changes in ADHD medication dispensing.

Indexed as

Attention Deficit Disorder with HyperactivityCentral Nervous System StimulantsMethylphenidateAdolescentChildChild, PreschoolDrug PrescriptionsFemaleHumansInfantMaleMental Health ServicesNetherlandsRetrospective StudiesYoung AdultCentral Nervous System StimulantsMethylphenidateADHD medicationDosagesDuration of useDutch youthIncidencePrevalencePsychostimulantsYouth Act

Identifiers

PMID40549174
PMCPMC12743109

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.