ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2025
Subclinical congestion assessed by whole-body bioelectrical impedance analysis in HFrEF outpatients.
Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic Value of Multifrequency Bioelectrical Impedance Analysis in Chronic Obstructive Pulmonary Disease: Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Prognostic value of bioelectrical impedance analysis in heart failure: A systematic review of congestion assessment and clinical outcomes.American heart journal plus : cardiology research and practice · 2026Review
- Advancing cardiovascular care-key insights from the Netherlands Heart Journal 2025.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026Article
- From guidelines to patient-centred action.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent congestion in heart failure (HF) carries a dismal prognosis. Bioimpedance analysis (BIA) non-invasively identifies extracellular water (ECW) redistribution associated with acute HF. However, its role in detecting subclinical congestion in HF outpatients still needs to be explored.
methodsEighty-three adult outpatients with HFrEF were recruited for a single-center prospective study. Segmental multi-frequency BIA was used to assess body composition and the extracellular-to-total body water ratio (ECW/TBW), a marker of fluid redistribution. Subclinical congestion was defined as ECW/TBW
resultsIn this cohort, 57% of patients had subclinical congestion. Higher congestion grades were associated with age, female sex, and comorbidities. ECW/TBW
conclusionsBIA detects subclinical congestion-a condition highly prevalent in outpatients with HFrEF. An increased ECW/TBW ratio correlates with established markers of congestion and is associated with adverse events in this population. These findings support the integration of BIA into routine HF care; however, further studies are needed to establish the clinical benefits of BIA-guided management and its impact on patient outcomes.
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