Observational studyJournal of ultrasound2025
Renal resistive index for the prediction of augmented renal clearance: a prospective observational study.
Observational study in Journal of ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Renal resistive ındex in augmented renal clearance: limitations of static assessment and the case for a dynamic approach.Journal of ultrasound · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAugmented renal clearance (ARC) is frequently observed in ICU patients and is associated with renal vascular changes. We hypothesized that the renal resistive index (RRI) could predict ARC. Secondary objectives included evaluating the correlation between RRI and creatinine clearance (CrCl), identifying risk factors for ARC, and assessing its impact on ICU outcomes such as length of stay and survival.
methodsThis prospective observational study included 108 adult ICU patients without kidney disease, enrolled within 24 h of admission. RRI measurement, 24-h CrCl, and ARC score calculation were performed on the first day of ICU stay. We analysed RRI's accuracy in predicting ARC and investigated associations with clinical variables and outcomes.
resultsRRI demonstrated high predictive accuracy for ARC (AUROC: 0.897, 95% CI 0.836-0.958). ARC prevalence was 38.9%. Significant risk factors for ARC included younger age, SOFA score, vasopressor use, trauma-related admissions, and diuretic use. A moderate negative correlation between RRI and CrCl was observed (r = - 0.541, p < 0.001). RRI showed superior predictive performance compared to the ARC score (p = 0.0008). ARC did not significantly affect ICU length of stay but was associated with improved ICU survival.
conclusionsRRI is a reliable predictor of ARC in ICU patients and can help identify patients at risk early. Combining RRI with risk factors such as age, trauma-related admissions, and severity of illness may improve ARC detection and guide therapeutic decisions.
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