ReviewClinical research in cardiology : official journal of the German Cardiac Society2025
Atrial functional mitral regurgitation: definition, features, and unknowns.
Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Combined Atrial Functional Mitral and Tricuspid Regurgitation in Atrial Fibrillation: Prevalence, Associated Factors, and Three-Dimensional Valve Remodeling.Journal of clinical medicine · 2026Article
- Atrial Secondary Mitral Regurgitation: Pathophysiology, Diagnosis, and Surgical Implications.Medicina (Kaunas, Lithuania) · 2026Review
- Changes in echocardiographic parameters and strain and outcomes following mitral valve repair: insight from new mitral regurgitation classifications.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atrial functional mitral regurgitation (AFMR) is a form of functional mitral regurgitation as yet insufficiently recognized and characterized. The driving cause is atrial, not ventricular dilatation, usually due to long-standing atrial fibrillation, and often in association with left ventricular diastolic dysfunction and heart failure with preserved ejection fraction. Increase in mitral annular area leads to loss of central coaptation of the leaflets. Because of the normal sized and normally or nearly normally contracting left ventricle, the amount of regurgitation is typically not more than moderate or moderate-to-severe by standard criteria. The time course of AFMR and the relation to symptoms have yet to be elucidated more clearly. There is a large overlap of symptoms and signs between AFMR and heart failure with preserved ejection fraction, making it likely that the role of AFMR in patients with heart failure has been underestimated. This review presents current concepts and published insights into this form of mitral regurgitation.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.