ArticleAddiction biology2025
Transient Elastography Increases Readiness for Change in Inpatients With Alcohol Use Disorder: The ELISA Pilot Study.
Article in Addiction biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Day-Level Mediators of Change in Brief Motivational Intervention for Alcohol Use and Liver Health.Research square · 2026Article
- Transient Elastography Increases Readiness for Change in Inpatients With Alcohol Use Disorder: The ELISA Pilot Study.Addiction biology · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Opportunistic interventions (OIs) are health events facilitated by healthcare providers through education that can motivate individuals to adopt risk-reducing behaviours. Our aim was to evaluate transient elastography (TE) as an OI in patients with AUD by assessing changes in validated psychometric scores (PS) of alcohol insight and readiness for change. In this prospective, proof-of-concept pilot study, patients with AUD without TE in the past year were enrolled from an inpatient addiction unit. At baseline, three PS assessing insight and readiness to change were administered: Hanil Alcohol Insight Scale (HAIS), revised Readiness Ruler (RR) and Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES-8A). TE was performed, interpreted, and followed by repeat PS testing. The primary outcome was change in PS. Secondary outcomes were prevalence of fibrosis and steatosis on TE, alcohol use and linkage to hepatology care. From 4 January 2022 to 4 January 2023, 23 patients were enrolled: mean age: 51 years (SD ± 12), 74% male, 61% White and all with severe AUD, and mean of 20 (± 9) daily drinks, 286 g (± 127 g) or 35.7 (± 15.9) units of alcohol, for a median of 14 years (IQR 10-21.5). After TE, there were significant increases in revised RR and SOCRATES-8A from 5 to 8.6 (± 2.1, p < 0.01) and 81.5 to 85.0 (± 8.0, p = 0.04), respectively, indicating improved motivation and readiness for change. HAIS did not change: 11.1-11.0 (± 3, p = 0.36). Cirrhosis and steatosis grade ≥ 2 were detected in 4/23 (17%) and 8/23 (35%), respectively. In this pilot study, performing and interpreting results of TE to inpatients with AUD increase readiness for change and efficiently detects advanced fibrosis.
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