Evidence map›Paper›PMID 40548721›Full record

ArticlemSystems2025

From stool to sequence: decoding the human diet with FoodSeq.

Dorothy K Superdock, Brianna L Petrone, Michelle C Kirtley, Lawrence A David

Abstract read
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dorothy K Superdock *Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0001-5348-3307
Brianna L Petrone *Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0003-4778-7595
Michelle C KirtleyDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0009-0006-2438-6990
Lawrence A DavidDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-3570-4767

Funding

Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
DUKE TRAINING GRANT IN DIGESTIVE DISEASES AND NUTRITIONT32DK007568 · NIDDK · DUKE UNIVERSITY · PI Katherine Garman, Rodger A. Liddle · 1988 to 2026
$5.6M
Personalizing prebiotic therapies that target human gut microbiotaR01DK116187 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2018 to 2026
$3.7M
Using DNA sequencing to assess dietary species richnessR01DK128611 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2022 to 2026
$2.9M
NIDDK NIH HHS R01 DK116187NIDDK NIH HHS R01 DK128611NIDDK NIH HHS T32 DK007568NIGMS NIH HHS T32 GM145449
6 · The paper itself

Abstract

Diet plays a pivotal role in human health and disease. Yet, nutrition studies have long relied on self-report methods for collecting dietary intake data despite known limitations. Although new technologies for dietary intake assessment and biomarker identification are in development, the integration of genomics has been limited. DNA metabarcoding, a method that identifies many taxa at once using a short region of DNA, has recently been adapted for use in stool samples from free-living humans. This process, called FoodSeq, provides an objective way to determine the foods people eat. FoodSeq has numerous advantages over self-report methods, is a necessary complement to other methodological innovations in dietary intake assessment, and holds considerable promise for application on an epidemiologic scale, enabling more robust analysis of global dietary patterns.

Indexed as

DietDNA Barcoding, TaxonomicFecesHumansbiomarkerdietDNAfoodseqgenomicsmetabarcodingnutritionsequencingstool

Identifiers

PMID40548721
PMCPMC12282114

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.