Evidence map›Paper›PMID 40548718›Full record

ArticleAntimicrobial agents and chemotherapy2025

Arylmethylamino steroid compound 1o interferes with

Eric Springer, Kim C Heimsch, Niklas Sidiropoulos, Jacomina Krijnse Locker, Jude M Przyborski

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric SpringerBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, Giessen, Germany.ORCID 0000-0002-8092-1453
Kim C HeimschBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, Giessen, Germany.
Niklas SidiropoulosBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, Giessen, Germany.
Jacomina Krijnse LockerJustus Liebig University, Giessen, Germany.
Jude M PrzyborskiBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, Giessen, Germany.ORCID 0000-0002-3494-7767

Funding

Hessisches Ministerium für Wissenschaft und Kunst (Hessian Ministry for Science and Art) LOEWE-DRUID
6 · The paper itself

Abstract

The anti-parasitic compound arylmethylamino steroid 1o (1o) is a promising drug candidate with low nanomolar activity against the malaria parasite

Indexed as

AntimalarialsHemoglobinsPlasmodium falciparumAdenosine TriphosphateChloroquineErythrocytesHemeHumansHydrogen-Ion ConcentrationLife Cycle StagesMefloquineTrophozoitesVacuolesAdenosine TriphosphateAntimalarialsChloroquineHemeHemoglobinsMefloquinearylmethylamino steroidsATeam1.03YEMKATPhemehemoglobinmalariaPlasmodiumsfpHluorin

Identifiers

PMID40548718
PMCPMC12327009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.