Evidence map›Paper›PMID 40548584›Full record

ArticleAnnals of surgery2025

Robot-assisted and Laparoscopic Extended Left Pancreatectomy: A Pan-European Multicenter Propensity-score Matched Analysis.

Caro L Bruna, Tess van Ramshorst, Jony van Hilst, Alberto Balduzzi, Bas Groot Koerkamp, Safi Dokmak, Olivier R Busch, Frederik Berrevoet, Marco Ramera, Bjørn Edwin and 17 more

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Article in Annals of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Caro L BrunaDepartment of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.
Tess van RamshorstDepartment of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.
Jony van HilstAmsterdam UMC, location University of Amsterdam, Department of Surgery, Amsterdam, The Netherlands.
Alberto BalduzziDepartment of Surgery, Pancreas Institute, Verona University Hospital, Verona, Italy.
Bas Groot KoerkampDepartment of Surgery, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Safi DokmakDepartment of HPB Surgery and Liver Transplantation, Beaujon Hospital, University Paris Cite, Clichy, France.
Olivier R BuschAmsterdam UMC, location University of Amsterdam, Department of Surgery, Amsterdam, The Netherlands.
Frederik BerrevoetDepartment of General and Hepatopancreatobiliary Surgery and Liver Transplantation, Ghent University Hospital, Ghent, Belgium.
Marco RameraDepartment of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.
Bjørn EdwinThe Intervention Centre and Department of HPB Surgery, Oslo University Hospital, Also Institute of Medicine, University of Oslo, Norway.
Ugo BoggiDepartment of Surgery, University Hospital of Pisa, Pisa, Italy.
Sebastiaan FestenDepartment of Surgery, OLVG Hospital, Amsterdam, The Netherlands.
Uwe A WittelMedical Center, University of Freiburg, Department of General and Visceral Surgery, Freiburg, Germany.
Joaquim BalsellsDepartment of HPB and Transplant Surgery, Vall d'Hebron University Hospital, Barcelona, Spain.
Gregory SergeantDepartment of Digestive and Hepatobiliary/Pancreatic Surgery, Jessa Hospital, Faculty of Medicine and Health Sciences, Hasselt, Belgium.
Giovanni FerrariDepartment of Surgery, Niguarda Hospital, Milan, Italy.
Esther A BieselMedical Center, University of Freiburg, Department of General and Visceral Surgery, Freiburg, Germany.
Misha D P LuyerDepartment of Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Peter B van den BoezemDepartment of Surgery, Radboud Medical Centre, Nijmegen, The Netherlands.
Santiago Lopez-BenHepatobiliary and Pancreatic Surgery Unit, Department of Surgery, Dr. Josep Trueta Hospital, IdIBGi, Girona, Spain.
Miha PetričUniversity Medical Centre Ljubljana, Department of Abdominal Surgery, University of Ljubljana, Ljubljana, Slovenia.
Zahir SoonawallaDepartment of Surgery, Oxford University Hospital NHS Foundation Trust, Oxford, United Kingdom.
Roeland de WildeDepartment of Surgery, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Beatrice AussilhouDepartment of HPB Surgery and Liver Transplantation, Beaujon Hospital, University Paris Cite, Clichy, France.
Marc G BesselinkAmsterdam UMC, location University of Amsterdam, Department of Surgery, Amsterdam, The Netherlands.
Mohammad Abu HilalDepartment of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare postoperative outcomes after extended robot-assisted left pancreatectomy (e-RLP) and extended laparoscopic left pancreatectomy (e-LLP). SUMMARY BACKGROUND DATA: The implementation of RLP is increasing worldwide with expanding indications, resulting in more extended resections. However, the use of e-RLP has not been investigated before.

methodsInternational study including consecutive patients after e-RLP and e-LLP for all indications in 19 European countries (2012-2022). Extended resection was defined according to the ISGPS definition. Propensity score matching (PSM) was performed in a 1:1 ratio with a caliper width of 0.1. Primary endpoint was major morbidity (Clavien-Dindo grade ≥III complications).

resultsOverall, 514 patients were included from 72 centers (152 e-RLPs; 362 e-LLPs). Before PSM, e-RLP patients had more tail tumors (69.4% vs 50.0%, P=0.001), vascular involvement (30.3% vs 16.3%, P<0.001) and >2 additional organ resections (28.5% vs 10.7%, P<0.001), with comparable major morbidity rates (27.0% vs 27.0%, P=0.991) and a lower conversion rate (15.1% vs 23.5%, P=0.033), compared to e-LLP. After PSM, 119 e-RLP patients were matched to 119 e-LLP patients. No significant differences were observed in major morbidity (23.5% vs 26.5%, P=0.599), blood loss (200 vs 150 mL, P=0.835), conversion rate (16.0% vs 20.0%, P=0.422), 30-day/in-hospital mortality (1.7% vs 3.4%, P=0.408), and hospital stay (median 7 vs 7 days, P=0.906). E-RLP had longer operative times (median 277 vs 228 min, P<0.001).

conclusionsThis pan-European cohort study found no significant differences in the outcomes among matched patients undergoing e-RLP and e-LLP, although e-RLP was associated with a longer operative time. The robot-assisted approach is used for more extensive resections with a comparable major morbidity rate compared to laparoscopy.

Indexed as

distal pancreatectomyextended resectionsleft pancreatectomyminimally invasive distal pancreatectomyminimally invasive surgerypostoperative pancreatic fistula

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.