Evidence map›Paper›PMID 40548296›Full record

ArticleMediators of inflammation2025

Immune Regulation and ECM-Related Pathway Enrichment Reveal ATP2A3 as a Prognostic Biomarker for Nonspecific Orbital Inflammation: An Integrated Machine Learning and Mendelian Randomization Analysis.

Zixuan Wu, Xi Long, Kang Tan, Xiaolei Yao, Qinghua Peng

Abstract read
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zixuan WuHunan University of Traditional Chinese Medicine, Changsha 410208, Hunan Province, China.ORCID https://orcid.org/0000-0002-2993-9949
Xi LongHunan University of Traditional Chinese Medicine, Changsha 410208, Hunan Province, China.
Kang TanHunan University of Traditional Chinese Medicine, Changsha 410208, Hunan Province, China.
Xiaolei YaoDepartment of Ophthalmology, The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Changsha 410007, Hunan Province, China.ORCID https://orcid.org/0000-0003-0680-9698
Qinghua PengHunan University of Traditional Chinese Medicine, Changsha 410208, Hunan Province, China.ORCID https://orcid.org/0000-0002-9378-1330

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Extracellular MatrixInflammationMachine LearningSarcoplasmic Reticulum Calcium-Transporting ATPasesBiomarkersGene Expression ProfilingGene Regulatory NetworksHumansPrognosisBiomarkersSarcoplasmic Reticulum Calcium-Transporting ATPasesATP2A3autoimmune inflammatory disorderLasso regressionMendelian randomizationnonspecific orbital inflammation (NSOI)

Identifiers

PMID40548296
PMCPMC12181670

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.