Evidence map›Paper›PMID 40548292›Full record

ArticleDEN open2026

Artificial Intelligence-assisted Endoscopy and Examiner Confidence: A Study on Human-Artificial Intelligence Interaction in Barrett's Esophagus (With Video).

David Roser, Michael Meinikheim, Anna Muzalyova, Robert Mendel, Christoph Palm, Andreas Probst, Sandra Nagl, Markus W Scheppach, Christoph Römmele, Elisabeth Schnoy and 4 more

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David RoserDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.ORCID https://orcid.org/0009-0006-4676-4999
Michael MeinikheimDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Anna MuzalyovaDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Robert MendelRegensburg Medical Image Computing (ReMIC), Ostbayerische Technische Hochschule Regensburg Regensburg Germany.
Christoph PalmRegensburg Medical Image Computing (ReMIC), Ostbayerische Technische Hochschule Regensburg Regensburg Germany.
Andreas ProbstDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Sandra NaglDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Markus W ScheppachDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Christoph RömmeleDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Elisabeth SchnoyDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Nasim ParsaDivision of Gastroenterology and Hepatology Mayo Clinic Scottsdale USA.
Michael F ByrneSatisfai Health Vancouver Canada.
Helmut MessmannDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.
Alanna EbigboDepartment of Gastroenterology University Hospital Augsburg Augsburg Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Despite high stand-alone performance, studies demonstrate that artificial intelligence (AI)-supported endoscopic diagnostics often fall short in clinical applications due to human-AI interaction factors. This video-based trial on Barrett's esophagus aimed to investigate how examiner behavior, their levels of confidence, and system usability influence the diagnostic outcomes of AI-assisted endoscopy. Methods: The present analysis employed data from a multicenter randomized controlled tandem video trial involving 22 endoscopists with varying degrees of expertise. Participants were tasked with evaluating a set of 96 endoscopic videos of Barrett's esophagus in two distinct rounds, with and without AI assistance. Diagnostic confidence levels were recorded, and decision changes were categorized according to the AI prediction. Additional surveys assessed user experience and system usability ratings. Results: AI assistance significantly increased examiner confidence levels ( Conclusions: Our findings highlight the pivotal function of examiner behavior in AI-assisted endoscopy. To fully realize the benefits of AI, implementing explainable AI, improving user interfaces, and providing targeted training are essential. Addressing these factors could enhance diagnostic accuracy and confidence in clinical practice.

Indexed as

AIartificial intelligenceBarrett's esophagusendoscopyHAII

Identifiers

PMID40548292
PMCPMC12178752

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.