ReviewFrontiers in veterinary science2025
An overview of natural herbal extracts and compounds for combating porcine epidemic diarrhea virus.
Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Antiviral effects of Codonopsis pilosula extract and its bioactive components against porcine epidemic diarrhea virus in vitro via the AMPK/mTOR pathway.BMC veterinary research · 2026Article
- Cross-Talk Between Pyroptosis and Ferroptosis Promotes Intestinal Inflammation and Barrier Failure During PEDV Infection.Biomolecules · 2026Article
- Salvianolic acid A exerts antiviral effects by targeting the S protein, a virulence factor of porcine epidemic diarrhea virus.Journal of virology · 2026Article
- Flavonoids: biological activities, nutritional and immunological aspects, therapeutic potential, food applications, and human health benefits-A comprehensive review.Frontiers in nutrition · 2026Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Porcine epidemic diarrhea virus (PEDV) is the etiological agent responsible for the acute infectious intestinal disease known as porcine epidemic diarrhea (PED), which results in severe diarrhea in piglets and causes substantial economic losses to the global swine industry. Currently, no specific therapeutic agent is available for the clinical treatment of PEDV, highlighting the urgent need to screen antiviral compounds and investigate antiviral mechanisms to develop effective antiviral therapies. Using active natural ingredients in animal husbandry represents a significant contemporary trend. Natural herbal products offer numerous advantages, including abundant availability, diverse biological activities, and low toxicity and side effects, as well as a reduced likelihood of developing drug resistance. These attributes position them as valuable resources for the development of effective anti-PEDV drugs. This paper provides a comprehensive review of the current research on the inhibitory effects of herbal monomers (isolated compounds), single-herb extracts, and compound herbal formulations (derived from research) against PEDV. The aim is to establish a theoretical foundation for the screening and development of therapeutic and prophylactic agents targeting PEDV.
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Registered trials
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