Evidence map›Paper›PMID 40548247›Full record

ArticleFrontiers in veterinary science2025

High seroprevalence of SARS-CoV-2 in cats linked to human infection in a Latin American country with elevated COVID-19 transmission and mortality.

Alexandra Ulloa, Maritza Cordero-Ortiz, Luis M Jara, Francesca Schiaffino, Cusi Ferradas, Camila Sánchez-Carrión, Ana Martínez-Vela, Jesús Hernández, Luis G Giménez-Lirola

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandra Ulloa *Facultad de Medicina Veterinaria y Zootecnia, Universidad Peruana Cayetano Heredia, Lima, Peru.
Maritza Cordero-Ortiz *Laboratorio de Inmunología, Centro de Investigación en Alimentación y Desarrollo, A.C., Hermosillo, Mexico.
Luis M Jara *Facultad de Medicina Veterinaria y Zootecnia, Universidad Peruana Cayetano Heredia, Lima, Peru.
Francesca SchiaffinoFacultad de Medicina Veterinaria y Zootecnia, Universidad Peruana Cayetano Heredia, Lima, Peru.
Cusi FerradasUnidad de Investigación en Enfermedades Emergentes y Cambio Climático (Emerge), Facultad de Salud Pública y Administración, Universidad Peruana Cayetano Heredia, Lima, Peru.
Camila Sánchez-CarriónClinica Veterinaria Gatuario, Lima, Peru.
Ana Martínez-VelaClinica Veterinaria Los Dominicos, Lima, Peru.
Jesús HernándezLaboratorio de Inmunología, Centro de Investigación en Alimentación y Desarrollo, A.C., Hermosillo, Mexico.
Luis G Giménez-LirolaDepartment of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.

Funding

Peru Infectious Diseases Epidemiology Research Training ConsortiumD43TW007393 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Andres G Lescano · 2005 to 2026
$5.9M
Genomic Epidemiology of Campylobacter in Poultry to Enable the Effective Control of Human Campylobacteriosis in a Middle Income CountryK43TW012298 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Francesca Schiaffino · 2022 to 2026
$811k
FIC NIH HHS D43 TW007393FIC NIH HHS K43 TW012298
6 · The paper itself

Abstract

Introduction: SARS-CoV-2 has been shown to infect various animal species, including companion animals such as cats. Although direct transmission from cats to humans has not been confirmed, monitoring the prevalence of infection in these animals remains critical as susceptible hosts to SARS-CoV-2, particularly in regions with high COVID-19 case numbers. This study aimed to evaluate the seroprevalence of SARS-CoV-2 in cats during the first wave of the COVID-19 pandemic in Lima, Peru. Methods: Serum samples from 544 cats, collected between 2020 and 2021, were tested for antibodies using a double antigen sandwich ELISA targeting the receptor-binding protein domain (RBD) and the nucleocapsid (N) proteins. This ELISA has a sensitivity of 80% and a specificity of 100%. Results: A seroprevalence of 43.8% was observed, with higher rates in females (63.9%), kittens (51.3%), and the Domestic Shorthair breed (93.2%). Among owners diagnosed with COVID-19, 95.5% of their cats were seropositive, with no cross-reactivity observed for other common feline diseases. Conclusion: These findings suggest significant SARS-CoV-2 exposure and possible infection in cats during the early pandemic phase in Peru. The high seroprevalence observed highlights the need for ongoing surveillance of companion animals, especially in regions with high human infection rates.

Indexed as

antibodiescatsCOVID-19ELISASARS-CoV-2seroprevalence

Identifiers

PMID40548247
PMCPMC12178845

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.