Evidence map›Paper›PMID 40548179›Full record

ArticleFood science & nutrition2025

The Alleviative Effect of Naringin Against Cardiovascular Dysfunction and Remodeling in Hypertensive Rats by Suppressing the Angiotensin II Pathway.

Juthamas Khamseekaew, Metee Iampanichakul, Prapassorn Potue, Putcharawipa Maneesai, Panot Tangsucharit, Siwayu Rattanakanokchai, Poungrat Pakdeechote

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juthamas KhamseekaewDepartment of Physiology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Metee IampanichakulDepartment of Physiology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Prapassorn PotueDepartment of Physiology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Putcharawipa ManeesaiDepartment of Physiology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Panot TangsucharitDepartment of Pharmacology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Siwayu RattanakanokchaiFaculty of Veterinary Medicine Khon Kaen University Khon Kaen Thailand.
Poungrat PakdeechoteDepartment of Physiology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.ORCID https://orcid.org/0000-0001-8114-5954

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naringin is an essential citrus flavonoid with numerous biological benefits. However, its influence on the heart and aorta during hypertension is poorly understood. This study aimed to determine whether naringin could alleviate left ventricular (LV)-aortic dysfunction and remodeling in hypertensive rats generated using

Indexed as

cardiovascular dysfunction and remodelinghypertensionnaringinrenin‐angiotensin system oxidative stress

Identifiers

PMID40548179
PMCPMC12178940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.