ArticleApplied biosafety : journal of the American Biological Safety Association2025
The World Needs a PEPP Policy that Addresses Biosafety Loopholes Highlighted by the COVID-19 Pandemic.
Article in Applied biosafety : journal of the American Biological Safety Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Abstract
The new U.S. government policy for oversight of dual-use research of concern and pathogens with enhanced pandemic potential (PEPP) focuses on federally funded research projects that are predicted by the funding applicant to have a nontrivial likelihood of generating a PEPP. This leaves a considerable gap in oversight of nonfederally funded work and research on novel pathogens. The prediction of pandemic risk arising from novel experiments is difficult even for multidisciplinary teams of experts, and a self-reporting system is inadequate as evidenced by past incidents. Creating an independent organization for oversight, inspection, and investigation of research projects regardless of funding source will ensure consistency and transparency in policy implementation and help to build knowledge and best practices for mitigating the risks of accidental outbreaks.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.